ArticleJournal of the American Heart Association2022
Predictors and Outcomes of Heart Failure With Preserved Ejection Fraction in Patients With a Left Ventricular Ejection Fraction Above or Below 60.
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed.
- The impact of atrial fibrillation on clinical outcomes in heart failure with mid-range and preserved ejection fraction patients.Heart rhythm · 2024Trial
- Prognostic value of potential energy derived from noninvasive pressure-volume loop analysis in heart failure with preserved ejection fraction.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Left ventricular untwist determines intradialytic hemodynamics and outcomes in mildly reduced and preserved ejection fraction patients.Physiological reports · 2025Article
- [Left Ventricular Structural and Functional Changes in Obese Subjects With Preserved Left Ventricular Ejection Fraction After Bariatric Surgery: Assessment With Cardiac Magnetic Resonance Imaging].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Article
- Time to Reconsider Ejection Fraction in Heart Failure: Reclassification Needed Beyond Ejection Fraction.JACC. Asia · 2023Article
- Association of left ventricular strain-volume loop characteristics with adverse events in patients with heart failure with preserved ejection fraction.European heart journal. Cardiovascular Imaging · 2023Article
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Although potential therapeutic candidates for heart failure with preserved ejection fraction (HFpEF) are emerging, it is still unclear whether they will be effective in patients with left ventricular ejection fraction (LVEF) of 60% or higher. Our aim was to identify the clinical characteristics of these patients with HFpEF by comparing them to patients with LVEF below 60%. Methods and Results From a multicenter, prospective, observational cohort (PURSUIT-HFpEF [Prospective Multicenter Obsevational Study of Patients with Heart Failure with Preserved Ejection Fraction]), we investigated 812 consecutive patients (median age, 83 years; 57% women), including 316 with 50% ≤ LVEF <60% and 496 with 60% ≤ LVEF, and compared the clinical backgrounds of the 2 groups and their prognoses for cardiac mortality or HF readmission. Two hundred four adverse outcomes occurred at a median of 366 days. Multivariable Cox regression tests adjusted for age, sex, heart rate, atrial fibrillation, estimated glomerular filtration rate, N-terminal pro-B-type natriuretic peptide, and prior heart failure hospitalization revealed that systolic blood pressure (hazard ratio [HR], 0.925 [95% CI, 0.862-0.992];
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