Evidence map›Paper›PMID 35904194›Full record

ArticleJournal of the American Heart Association2022

Natural Language Processing to Improve Prediction of Incident Atrial Fibrillation Using Electronic Health Records.

Jeffrey M Ashburner, Yuchiao Chang, Xin Wang, Shaan Khurshid, Christopher D Anderson, Kumar Dahal, Dana Weisenfeld, Tianrun Cai, Katherine P Liao, Kavishwar B Wagholikar and 4 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Predicting post-stroke cognitive impairment using electronic health record data.International journal of stroke : official journal of the International Stroke Society · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Artificial Intelligence Technologies in Cardiology.Journal of cardiovascular development and disease · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jeffrey M AshburnerDivision of General Internal Medicine Massachusetts General Hospital Boston MA.ORCID 0000-0002-5600-3492
Yuchiao ChangDivision of General Internal Medicine Massachusetts General Hospital Boston MA.
Xin WangCardiovascular Research Center Massachusetts General Hospital Boston MA.
Shaan KhurshidCardiovascular Research Center Massachusetts General Hospital Boston MA.ORCID 0000-0002-2840-4539
Christopher D AndersonDepartment of Neurology Brigham and Women's Hospital Boston MA.ORCID 0000-0002-0053-2002
Kumar DahalDepartment of Rheumatology, Inflammation, and Immunity Brigham and Women's Hospital Boston MA.
Dana WeisenfeldDepartment of Rheumatology, Inflammation, and Immunity Brigham and Women's Hospital Boston MA.
Tianrun CaiHarvard Medical School Boston MA.
Katherine P LiaoHarvard Medical School Boston MA.ORCID 0000-0002-4797-3200
Kavishwar B WagholikarHarvard Medical School Boston MA.ORCID 0000-0002-6219-861X
Shawn N MurphyHarvard Medical School Boston MA.
Steven J AtlasDivision of General Internal Medicine Massachusetts General Hospital Boston MA.
Steven A LubitzCardiovascular Research Center Massachusetts General Hospital Boston MA.ORCID 0000-0002-9599-4866
Daniel E SingerDivision of General Internal Medicine Massachusetts General Hospital Boston MA.ORCID 0000-0001-6145-4848

Funding

Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH)U01NS069763 · NINDS · UNIVERSITY OF CINCINNATI · PI ANDERSON, CHRISTOPHER DAVID, DEMEL, STACIE · 2010 to 2024
$34.2M
VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYticsP30AR072577 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Daniel Hal Solomon · 2017 to 2026
$9.8M
Sequencing Annotation and Functional Analysis in Risk of Intracerebral HemorrhageR01NS103924 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ANDERSON, CHRISTOPHER DAVID · 2018 to 2022
$3.4M
Genomics of Cardiac ArrhythmiasR01HL139731 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS · 2018 to 2022
$3.3M
Using Electrocardiogram Genetics to Inform Arrhythmia RiskR01HL157635 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS, MIRSHAHI, TOORAJ · 2022 to 2025
$2.9M
Identifying primary care patients at increased risk of atrial fibrillation for screening interventionsK01HL148506 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ASHBURNER, JEFFREY M · 2019 to 2023
$887k
NHLBI NIH HHS K01 HL148506NHLBI NIH HHS R01 HL139731NHLBI NIH HHS R01 HL157635NIAMS NIH HHS P30 AR072577NINDS NIH HHS R01 NS103924NINDS NIH HHS U01 NS069763
6 · The paper itself

Abstract

Background Models predicting atrial fibrillation (AF) risk, such as Cohorts for Heart and Aging Research in Genomic Epidemiology AF (CHARGE-AF), have not performed as well in electronic health records. Natural language processing (NLP) may improve models by using narrative electronic health record text. Methods and Results From a primary care network, we included patients aged ≥65 years with visits between 2003 and 2013 in development (n=32 960) and internal validation cohorts (n=13 992). An external validation cohort from a separate network from 2015 to 2020 included 39 051 patients. Model features were defined using electronic health record codified data and narrative data with NLP. We developed 2 models to predict 5-year AF incidence using (1) codified+NLP data and (2) codified data only and evaluated model performance. The analysis included 2839 incident AF cases in the development cohort and 1057 and 2226 cases in internal and external validation cohorts, respectively. The C-statistic was greater (

Indexed as

Atrial FibrillationNatural Language ProcessingCohort StudiesElectronic Health RecordsHumansIncidenceRisk Assessmentatrial fibrillationnatural language processingpredicted risk

Identifiers

PMID35904194
PMCPMC9375475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.