Evidence map›Paper›PMID 35904169›Full record

ArticleOncology reports2022

Correlation of treatment outcome in sanger/RT‑qPCR

Mojca Unk, Alenka Bombač, Barbara Jezeršek Novaković, Vida Stegel, Vita Šetrajčič Dragoš, Olga Blatnik, Gašper Klančar, Srdjan Novaković

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Precision Oncology in Gastrointestinal Stromal Tumors.Current oncology (Toronto, Ont.) · 2023
    Review
  5. Review
  6. GISTs withCancers · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mojca UnkFaculty of Medicine, University of Ljubljana, SI‑1000 Ljubljana, Slovenia.
Alenka BombačDepartment of Molecular Diagnostics, Institute of Oncology Ljubljana, SI‑1000 Ljubljana, Slovenia.
Barbara Jezeršek NovakovićFaculty of Medicine, University of Ljubljana, SI‑1000 Ljubljana, Slovenia.
Vida StegelDepartment of Molecular Diagnostics, Institute of Oncology Ljubljana, SI‑1000 Ljubljana, Slovenia.
Vita Šetrajčič DragošDepartment of Molecular Diagnostics, Institute of Oncology Ljubljana, SI‑1000 Ljubljana, Slovenia.
Olga BlatnikDepartment of Pathology, Institute of Oncology Ljubljana, SI‑1000 Ljubljana, Slovenia.
Gašper KlančarDepartment of Molecular Diagnostics, Institute of Oncology Ljubljana, SI‑1000 Ljubljana, Slovenia.
Srdjan NovakovićFaculty of Medicine, University of Ljubljana, SI‑1000 Ljubljana, Slovenia.
Institute of Oncology Ljubljana · SIUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with gastrointestinal stromal tumors (GIST), it has become mandatory to determine the driver mutation in order to predict the response to standard treatment with tyrosine kinase inhibitors (TKI). A total of 10‑15% of all GIST lack activating mutations in KIT proto‑oncogene, receptor tyrosine kinase (

Indexed as

Antineoplastic AgentsGastrointestinal Stromal TumorsHigh-Throughput Nucleotide SequencingHumansImatinib MesylateMutationProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-kitReceptor, Platelet-Derived Growth Factor alphaReceptor Protein-Tyrosine KinasesReproducibility of ResultsTreatment OutcomeAntineoplastic AgentsImatinib MesylateProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-kitReceptor, Platelet-Derived Growth Factor alphaReceptor Protein-Tyrosine Kinasesgastrointestinal stromal tumorsimatinibnext‑generation sequencingtyrosine kinase inhibitorswild‑type

Identifiers

PMID35904169
PMCPMC9351002
OpenAlexW4288096595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.