Evidence map›Paper›PMID 35903864›Full record

ReviewThoracic cancer2022

Successful restart of chemotherapy in a patient with primary mediastinal nonseminomatous germ cell tumor after COVID-19 infection.

Yuki Tanabe, Takehito Shukuya, Yuichi Nagata, Takayasu Watanabe, Koichi Seto, Rina Takahashi, Koichi Masuda, Keita Miura, Ken Tajima, Makoto Hiki and 3 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Thoracic cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yuki TanabeDepartment of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.ORCID 0000-0003-1463-2749
Takehito ShukuyaDepartment of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.ORCID 0000-0002-0972-4692
Yuichi NagataDepartment of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Takayasu WatanabeDepartment of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Koichi SetoClinical training center, Juntendo University Hospital, Tokyo, Japan.
Rina TakahashiClinical training center, Juntendo University Hospital, Tokyo, Japan.
Koichi MasudaDepartment of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Keita MiuraDepartment of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.ORCID 0000-0003-2685-5616
Ken TajimaDepartment of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Makoto HikiDepartment of Cardiovascular Biology and Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Takuo HayashiDepartment of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan.
Kenji SuzukiDepartment of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Kazuhisa TakahashiDepartment of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Juntendo University · JPJuntendo University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer patients are considered highly susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, it is not well known when chemotherapy can be safely restarted in cancer patients after coronavirus disease 2019 (COVID-19). Here, we describe the case of an 18-year-old man diagnosed with primary mediastinal nonseminomatous germ cell tumor (PMNSGCT) in which chemotherapy could be safely restarted after COVID-19. On day 11 of the third cycle of bleomycin, etoposide, plus cisplatin (BEP), he was diagnosed with mild COVID-19. On day 16 after the onset of COVID-19 (day 26 of third cycle of BEP), chemotherapy for his PMNSGCT was restarted. He received surgery after the fourth cycle of BEP without recurrence of COVID-19. Chemotherapy could be restarted and followed by surgery in this post-COVID-19 patient who had experienced mild illness after the discharge criteria were met and all symptoms had disappeared. We report this case with a review of the literature on restarting chemotherapy after SARS-CoV2 infection.

Indexed as

COVID-19AdolescentAntineoplastic Combined Chemotherapy ProtocolsBleomycinCisplatinEtoposideHumansMaleNeoplasms, Germ Cell and EmbryonalRNA, ViralSARS-CoV-2Testicular NeoplasmsBleomycinCisplatinEtoposideRNA, ViralchemotherapyCOVID-19PMNSGCTspost-COVID-19primary mediastinal nonseminomatous germ cell tumors

Identifiers

PMID35903864
PMCPMC9353416
OpenAlexW4288489908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.