Evidence map›Paper›PMID 35903569›Full record

ReviewCureus2022

Effect of Thyroxine and Thyrotropin on Bone Mineral Density in Postmenopausal Women: A Systematic Review.

Prakar Poudel, Roopa Chalasani, Mastiyage R Goonathilake, Sara Waqar, Sheeba George, Wilford Jean-Baptiste, Amina Yusuf Ali, Bithaiah Inyang, Feeba Sam Koshy, Kitty George and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Prakar PoudelResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Roopa ChalasaniResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Mastiyage R GoonathilakeResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sara WaqarResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sheeba GeorgeResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Wilford Jean-BaptisteResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Amina Yusuf AliResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Bithaiah InyangResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Feeba Sam KoshyResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Kitty GeorgeResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Lubna MohammedResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of thyroid hormones on bone mineral density in postmenopausal women has been reported but is not completely established. To better understand this relationship, this systematic review of the reported association, differences, and effects of thyroxine and/or thyrotropin levels on bone mineral density was conducted. An electronic literature search was conducted on MEDLINE, PMC, Google Scholar, Cochrane Library, and Science Direct from inception to April 2022; 20 studies were identified which include five quasi-experimental studies, three community cohort studies, and 12 hospital-based cross-sectional studies. Following an extensive evaluation, it was difficult to conclusively determine the association or effect of thyroxine or thyrotropin levels on bone mineral density in postmenopausal women. It is therefore suggested to conduct additional non-randomized or randomized control studies on this topic for the benefit of postmenopausal women. Particular attention should be given to the adjustment of age, body mass index, smoking status, alcohol consumption, and dietary calcium in future research on this topic for rigorous analysis.

Indexed as

bone mineral densitydexapostmenopausal womenthyrotropinthyroxine

Identifiers

PMID35903569
PMCPMC9325683
OpenAlexW4283581003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.