Evidence map›Paper›PMID 35903368›Full record

ReviewFrontiers in cellular neuroscience2022

The Role of Genetic Variants in the Susceptibility of Noise-Induced Hearing Loss.

Xue-Min Chen, Xin-Miao Xue, Ning Yu, Wei-Wei Guo, Shuo-Long Yuan, Qing-Qing Jiang, Shi-Ming Yang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Polymorphisms and NIHL: a systematic review and meta-analyses.Frontiers in cellular neuroscience · 2023
    Pooled it
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  20. Noise-Induced Hearing Loss.Journal of clinical medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xue-Min ChenMedical School of Chinese PLA, Beijing, China.
Xin-Miao XueMedical School of Chinese PLA, Beijing, China.
Ning YuSenior Department of Otolaryngology-Head & Neck Surgery, Chinese PLA General Hospital, Beijing, China.
Wei-Wei GuoSenior Department of Otolaryngology-Head & Neck Surgery, Chinese PLA General Hospital, Beijing, China.
Shuo-Long YuanSenior Department of Otolaryngology-Head & Neck Surgery, Chinese PLA General Hospital, Beijing, China.
Qing-Qing JiangSenior Department of Otolaryngology-Head & Neck Surgery, Chinese PLA General Hospital, Beijing, China.
Shi-Ming YangSenior Department of Otolaryngology-Head & Neck Surgery, Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNNational Clinical Research Center for Digestive Diseases · CNMinistry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noised-induced hearing loss (NIHL) is an acquired, progressive neurological damage caused by exposure to intense noise in various environments including industrial, military and entertaining settings. The prevalence of NIHL is much higher than other occupational injuries in industrialized countries. Recent studies have revealed that genetic factors, together with environmental conditions, also contribute to NIHL. A group of genes which are linked to the susceptibility of NIHL had been uncovered, involving the progression of oxidative stress, potassium ion cycling, cilia structure, heat shock protein 70 (HSP70), DNA damage repair, apoptosis, and some other genes. In this review, we briefly summarized the studies primary in population and some animal researches concerning the susceptible genes of NIHL, intending to give insights into the further exploration of NIHL prevention and individual treatment.

Indexed as

genesgenetic variantsnoised-induced hearing lossnoise preventionsusceptibility

Identifiers

PMID35903368
PMCPMC9315435
OpenAlexW4285034213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.