Evidence map›Paper›PMID 35903357›Full record

ArticleFrontiers in genetics2022

Landscape of Variability in Chemosensory Genes Associated With Dietary Preferences in Indian Population: Analysis of 1029 Indian Genomes.

P Prakrithi, Pankaj Jha, Jushta Jaiswal, Disha Sharma, Rahul C Bhoyar, Abhinav Jain, Mohamed Imran, Vigneshwar Senthilvel, Mohit Kumar Divakar, Anushree Mishra and 3 more

Abstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

P PrakrithiCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Pankaj JhaCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Jushta JaiswalCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Disha SharmaCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Rahul C BhoyarCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Abhinav JainCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Mohamed ImranCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Vigneshwar SenthilvelCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Mohit Kumar DivakarCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Anushree MishraCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Vinod ScariaCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Sridhar SivasubbuCSIR- Institute of Genomics and Integrative Biology, Delhi, India.
Mitali MukerjiCSIR- Institute of Genomics and Integrative Biology, Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perception and preferences for food and beverages determine dietary behaviour and health outcomes. Inherent differences in chemosensory genes, ethnicity, geo-climatic conditions, and sociocultural practices are other determinants. We aimed to study the variation landscape of chemosensory genes involved in perception of taste, texture, odour, temperature and burning sensations through analysis of 1,029 genomes of the IndiGen project and diverse continental populations. SNPs from 80 chemosensory genes were studied in whole genomes of 1,029 IndiGen samples and 2054 from the 1000 Genomes project. Population genetics approaches were used to infer ancestry of IndiGen individuals, gene divergence and extent of differentiation among studied populations. 137,760 SNPs including common and rare variants were identified in IndiGenomes with 62,950 novel (46%) and 48% shared with the 1,000 Genomes. Genes associated with olfaction harbored most SNPs followed by those associated with differences in perception of salt and pungent tastes. Across species, receptors for bitter taste were the most diverse compared to others. Three predominant ancestry groups within IndiGen were identified based on population structure analysis. We also identified 1,184 variants that exhibit differences in frequency of derived alleles and high population differentiation (F

Indexed as

chemosensory perceptionsfood preferencesgenetic diversitynutrigenomicspopulation differentiationprecision nutrition

Identifiers

PMID35903357
PMCPMC9315315

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.