Evidence map›Paper›PMID 35903338›Full record

ArticleFrontiers in pharmacology2022

Solamargine Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma by Decreasing LncRNA

Ying Meng, Mengli Jin, Dai Yuan, Yicheng Zhao, Xiangri Kong, Xuerui Guo, Xingye Wang, Juan Hou, Bingmei Wang, Wu Song and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ying MengCollege of Clinical Medicine, Changchun University of Chinese Medicine, Changchun, China.
Mengli JinCollege of Clinical Medicine, Changchun University of Chinese Medicine, Changchun, China.
Dai YuanCollege of Integrated Chinese and Western Medicine, College of Rehabilitation, Changchun University of Chinese Medicine, Changchun, China.
Yicheng ZhaoCollege of Clinical Medicine, Changchun University of Chinese Medicine, Changchun, China.
Xiangri KongAffiliated Hospital to Changchun University of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China.
Xuerui GuoSchool of Pharmacy, Jilin University, Changchun, China.
Xingye WangCollege of Integrated Chinese and Western Medicine, College of Rehabilitation, Changchun University of Chinese Medicine, Changchun, China.
Juan HouCollege of Integrated Chinese and Western Medicine, College of Rehabilitation, Changchun University of Chinese Medicine, Changchun, China.
Bingmei WangCollege of Clinical Medicine, Changchun University of Chinese Medicine, Changchun, China.
Wu SongCollege of Clinical Medicine, Changchun University of Chinese Medicine, Changchun, China.
Yong TangCollege of Clinical Medicine, Changchun University of Chinese Medicine, Changchun, China.
Changchun University of Chinese Medicine · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypopharyngeal squamous cell carcinoma (HSCC) is one of the high mortality cancers with a poor prognosis, which is driving the development of new chemotherapeutic agents. We identified the anticancer effects of a natural compound, solamargine (SM), on FaDU cells and explored its mechanism in terms of non-coding RNA. It was observed that SM inhibited the proliferation of FaDU cells with an IC

Indexed as

c-MycHOXA11-AShypopharyngeal squamous cell carcinomamiR-155solamargine

Identifiers

PMID35903338
PMCPMC9315292
OpenAlexW4285029705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.