Evidence map›Paper›PMID 35903295›Full record

ArticleDisease markers2022

Effect of Vitamin D Combined with Recombinant Human Growth Hormone in Children with Growth Hormone Deficiency.

Pingping Wang, Xuefeng Jin, Yan Zhang, Jianmei Zhang, Yunfang Li, Suhong Yang, Dan Li

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pingping WangDepartment of Endocrinology, Hangzhou Children's Hospital, No. 195 Wenhui Road, Gongshu District, Hangzhou, Zhejiang 310014, China.
Xuefeng JinDepartment of Gastroenterology, Hangzhou Children's Hospital, No. 195 Wenhui Road, Gongshu District, Hangzhou, Zhejiang 310014, China.
Yan ZhangDepartment of Endocrinology, Hangzhou Children's Hospital, No. 195 Wenhui Road, Gongshu District, Hangzhou, Zhejiang 310014, China.
Jianmei ZhangDepartment of Endocrinology, Hangzhou Children's Hospital, No. 195 Wenhui Road, Gongshu District, Hangzhou, Zhejiang 310014, China.
Yunfang LiDepartment of Endocrinology, Hangzhou Children's Hospital, No. 195 Wenhui Road, Gongshu District, Hangzhou, Zhejiang 310014, China.
Suhong YangDepartment of Endocrinology, Hangzhou Children's Hospital, No. 195 Wenhui Road, Gongshu District, Hangzhou, Zhejiang 310014, China.ORCID https://orcid.org/0000-0002-3542-7819
Dan LiHangzhou D.A. Medical Laboratory, Building 1, 329 Jinpeng Street, Sandun Town, Xihu District, Hangzhou, Zhejiang 310012, China.
Hangzhou Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Growth hormone deficiency (GHD) refers to the complete or partial lack of pituitary growth hormone synthesis and secretion. This study is aimed at investigating the efficacy of vitamin D and recombinant human growth hormone (rhGH) in children with GHD. Methods: A total of 100 children with GHD at our hospital were included between 1 Results: There were no significant differences in the bone age, growth rate, and height between the two groups before treatment. After 12 months of treatment, the bone age, growth rate, and height of the study group were significantly higher than those of the control group. After 12 months of treatment, the levels of serum BAP, PINP, and OC in the study group were significantly higher than those in the control group, while the levels of Conclusion: Combined rhGH and vitamin D treatment can promote growth and development, improve bone metabolism, and regulate IGF-1 and ghrelin levels.

Indexed as

Human Growth HormoneAlkaline PhosphataseChildCollagenGhrelinGrowth HormoneHumansInsulin-Like Growth Factor IOsteocalcinRecombinant ProteinsVitamin DVitaminsAlkaline PhosphataseCollagenGhrelinGrowth HormoneHuman Growth HormoneInsulin-Like Growth Factor IOsteocalcinRecombinant ProteinsVitamin DVitamins

Identifiers

PMID35903295
PMCPMC9325485
OpenAlexW4285798968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.