Evidence map›Paper›PMID 35903144›Full record

ArticleFrontiers in veterinary science2022

Does Orexin B-Binding Receptor 2 for Orexins Regulate Testicular and Epididymal Functions in Normal and Cryptorchid Dogs?

Caterina Squillacioti, Alessandra Pelagalli, Loredana Assisi, Anna Costagliola, Luc Van Nassauw, Nicola Mirabella, Giovanna Liguori

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Caterina SquillaciotiLaboratory of Anatomy, Department of Veterinary Medicine and Animal Productions, University of Napoli Federico II, Naples, Italy.
Alessandra PelagalliDepartment of Advanced Biomedical Sciences, University of Napoli Federico II, Naples, Italy.
Loredana AssisiDepartment of Biology, University of Napoli Federico II, Naples, Italy.
Anna CostagliolaLaboratory of Anatomy, Department of Veterinary Medicine and Animal Productions, University of Napoli Federico II, Naples, Italy.
Luc Van NassauwLaboratory of Human Anatomy and Embryology, Department ASTARC, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Nicola MirabellaLaboratory of Anatomy, Department of Veterinary Medicine and Animal Productions, University of Napoli Federico II, Naples, Italy.
Giovanna LiguoriLaboratory of Anatomy, Department of Veterinary Medicine and Animal Productions, University of Napoli Federico II, Naples, Italy.
University of Naples Federico II · ITNational Research Council · ITUniversity of Antwerp · BEUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orexins A (OXA) and B (OXB) and the receptors 1 (OX1R) and 2 (OX2R) for orexins are hypothalamic peptides found in several mammalian organs and participated to the control of a wide assortment of physiological and pathological functions. The distribution of OXA and OX1R has been extensively studied in the male gonad of mammals. Here, we examined the expression and localization of OXB and OX2R as well as their possible involvement in the regulation of testicular and epididymal functions, in healthy and cryptorchid dogs, employing some techniques such as immunohistochemistry, Western blotting, and real-time RT-PCR. In

Indexed as

cryptorchidismdogepididymisorexinssteroidogenesistestis

Identifiers

PMID35903144
PMCPMC9323089
OpenAlexW4285090985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.