Evidence map›Paper›PMID 35903114›Full record

ArticleFrontiers in neurology2022

Objective Observer vs. Patient Motor State Assessments Using the PD Home Diary in Advanced Parkinson's Disease.

Jonathan Timpka, Matthias Löhle, Alexander Bremer, Sofia Christiansson, Florin Gandor, Georg Ebersbach, Örjan Dahlström, Susanne Iwarsson, Maria H Nilsson, Alexander Storch and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Jonathan TimpkaDivision of Neurology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Matthias LöhleDepartment of Neurology, University of Rostock, Rostock, Germany.
Alexander BremerDepartment of Neurology, University of Rostock, Rostock, Germany.
Sofia ChristianssonDivision of Neurology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Florin GandorMovement Disorders Clinic, Beelitz-Heilstätten, Germany.
Georg EbersbachMovement Disorders Clinic, Beelitz-Heilstätten, Germany.
Örjan DahlströmDepartment of Behavioural Sciences and Learning, Linköping University, Linköping, Sweden.
Susanne IwarssonDepartment of Health Sciences, Lund University, Lund, Sweden.
Maria H NilssonDepartment of Health Sciences, Lund University, Lund, Sweden.
Alexander StorchDepartment of Neurology, University of Rostock, Rostock, Germany.
Per OdinDivision of Neurology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
German Center for Neurodegenerative Diseases · DELund University · SESkåne University Hospital · SELinköping University · SENeurologisches Fachkrankenhaus für Bewegungsstörungen/Parkinson · DEOtto-von-Guericke University Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Parkinson Disease (PD) Home Diary (HD) is a commonly used clinical outcome measure, but it has not been extensively compared to direct assessments by experienced observers. Objective: Validation of patient-reported HD by investigating the agreement between motor state assessments by patients and observers. Methods: This observational study included patients with PD and motor fluctuations. Observers were physicians or research nurses. Patients completed a screening visit, one day of diary ratings at home, and then two days of ratings on-site during which patients and observers simultaneously judged the participants' motor state. Results: Observers and 40 patients completed 1,288 pairs of half-hourly blinded motor state assessments. There were significant differences between observer and patient ratings ( Conclusion: There were significant differences between observer and patient ratings. Patients and observers generally agreed on when the patients was in the "On" state (with or without dyskinesia). Patient ratings on the hour level seem to be influenced by other aspects of the patients' experience than the observed motor state, but assessment of daily time spent in the different motor state provides reasonable reliability.

Indexed as

clinical trialsmotor fluctuationsParkinson diseaseParkinson disease home diarypatient reported outcome (PRO) measures

Identifiers

PMID35903114
PMCPMC9321639
OpenAlexW4285035314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.