Evidence map›Paper›PMID 35902915›Full record

ArticleCell & bioscience2022

Arcuate AgRP, but not POMC neurons, modulate paraventricular CRF synthesis and release in response to fasting.

Alan Carlos Alves Fernandes, Franciane Pereira de Oliveira, Gimena Fernandez, Luane da Guia Vieira, Cristiane Gugelmin Rosa, Taís do Nascimento, Suzelei de Castro França, Jose Donato, Kristen R Vella, Jose Antunes-Rodrigues and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Cell & bioscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Alan Carlos Alves Fernandes *Department of Biotechnology, University of Ribeirao Preto, Ribeirão Prêto, SP, 14096-900, Brazil.
Franciane Pereira de Oliveira *Department of Biophysics, Paulista Medical School, Federal University of Sao Paulo, São Paulo, SP, CEP 04023-062, Brazil.
Gimena FernandezLaboratory of Neurophysiology of the Multidisciplinary Institute of Cell Biology [IMBICE, Argentine Research Council (CONICET) and Scientific Research Commission, Province of Buenos Aires (CIC-PBA), National University of La Plata, La Plata, 403, Buenos Aires, Argentina.
Luane da Guia VieiraDepartment of Biotechnology, University of Ribeirao Preto, Ribeirão Prêto, SP, 14096-900, Brazil.
Cristiane Gugelmin RosaDepartment of Biotechnology, University of Ribeirao Preto, Ribeirão Prêto, SP, 14096-900, Brazil.
Taís do NascimentoDepartment of Biotechnology, University of Ribeirao Preto, Ribeirão Prêto, SP, 14096-900, Brazil.
Suzelei de Castro FrançaDepartment of Biotechnology, University of Ribeirao Preto, Ribeirão Prêto, SP, 14096-900, Brazil.
Jose DonatoDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, SP, 05508-000, Brazil.
Kristen R VellaDepartment of Endocrinology, Diabetes and Metabolism and the Weill Center for Metabolic Health, Weill Cornell Medical College, New York, NY, 10021, USA.
Jose Antunes-RodriguesDepartment of Physiology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirão Prêto, SP, 14049-900, Brazil.
André Souza MecawiDepartment of Biophysics, Paulista Medical School, Federal University of Sao Paulo, São Paulo, SP, CEP 04023-062, Brazil.
Mario PerelloLaboratory of Neurophysiology of the Multidisciplinary Institute of Cell Biology [IMBICE, Argentine Research Council (CONICET) and Scientific Research Commission, Province of Buenos Aires (CIC-PBA), National University of La Plata, La Plata, 403, Buenos Aires, Argentina.
Lucila Leico Kagohara EliasDepartment of Physiology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirão Prêto, SP, 14049-900, Brazil.
Rodrigo RoratoDepartment of Biotechnology, University of Ribeirao Preto, Ribeirão Prêto, SP, 14096-900, Brazil. rorato@unifesp.br.ORCID http://orcid.org/0000-0002-1327-9501
Universidade de Ribeirão Preto · BRUniversidade de São Paulo · BRConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidade Federal de São Paulo · BRCornell University · US

Funding

Regulation of thyroid hormone levels by central and peripheral pathwaysK01DK091403 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI VELLA, KRISTEN RACHEL · 2012 to 2014
$432k
Consejo Nacional de Investigaciones Científicas y Técnicas PUE-2017Conselho Nacional de Desenvolvimento Científico e Tecnológico 309882/2020-6Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.474642-2020-00Fondo para la Investigación Científica y Tecnológica PICT2016-1084Fondo para la Investigación Científica y Tecnológica PICT2017-3196Fondo para la Investigación Científica y Tecnológica PICT2019-3054Fundação de Amparo à Pesquisa do Estado de São Paulo 2016/17968-6Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão 2019/27581-0NIDDK NIH HHS K01 DK091403
6 · The paper itself

Abstract

backgroundThe activation of the hypothalamic-pituitary-adrenal (HPA) axis is essential for metabolic adaptation in response to fasting. However, the neurocircuitry connecting changes in the peripheral energy stores to the activity of hypothalamic paraventricular corticotrophin-releasing factor (CRF

resultsWe observed increased plasma corticosterone levels associate with increased CRF

conclusionOur data indicate that AgRP

Indexed as

AgRPCRFDREADDFastingHPA axis

Identifiers

PMID35902915
PMCPMC9331576
OpenAlexW4288080792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.