Evidence map›Paper›PMID 35902583›Full record

ArticleNature communications2022

Protein shape sampled by ion mobility mass spectrometry consistently improves protein structure prediction.

S M Bargeen Alam Turzo, Justin T Seffernick, Amber D Rolland, Micah T Donor, Sten Heinze, James S Prell, Vicki H Wysocki, Steffen Lindert

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
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  17. Review
  18. A Flexible, Modular Platform for Multidimensional Ion Mobility of Native-like Ions.Journal of the American Society for Mass Spectrometry · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S M Bargeen Alam TurzoDepartment of Chemistry and Biochemistry and Resource for Native Mass Spectrometry Guided Structural Biology, Ohio State University, Columbus, OH, 43210, USA.
Justin T SeffernickDepartment of Chemistry and Biochemistry and Resource for Native Mass Spectrometry Guided Structural Biology, Ohio State University, Columbus, OH, 43210, USA.
Amber D RollandDepartment of Chemistry and Biochemistry and Materials Science Institute, University of Oregon, Eugene, OR, 97403, USA.ORCID 0000-0002-7905-8250
Micah T DonorDepartment of Chemistry and Biochemistry and Materials Science Institute, University of Oregon, Eugene, OR, 97403, USA.
Sten HeinzeDepartment of Chemistry and Biochemistry and Resource for Native Mass Spectrometry Guided Structural Biology, Ohio State University, Columbus, OH, 43210, USA.
James S PrellDepartment of Chemistry and Biochemistry and Materials Science Institute, University of Oregon, Eugene, OR, 97403, USA.
Vicki H WysockiDepartment of Chemistry and Biochemistry and Resource for Native Mass Spectrometry Guided Structural Biology, Ohio State University, Columbus, OH, 43210, USA.ORCID 0000-0003-0495-2538
Steffen LindertDepartment of Chemistry and Biochemistry and Resource for Native Mass Spectrometry Guided Structural Biology, Ohio State University, Columbus, OH, 43210, USA. lindert.1@osu.edu.ORCID 0000-0002-3976-3473

Funding

Waters Select Series Cyclic IMS for P41 Native MS Resource Application to Alzheimer's DiseaseP41GM128577 · NIGMS · OHIO STATE UNIVERSITY · PI SOMOGYI, ARPAD · 2018 to 2022
$7.6M
NIGMS NIH HHS P41 GM128577
6 · The paper itself

Abstract

Ion mobility (IM) mass spectrometry provides structural information about protein shape and size in the form of an orientationally-averaged collision cross-section (CCS

Indexed as

Ion Mobility SpectrometryProteinsAlgorithmsMass SpectrometryProteins

Identifiers

PMID35902583
PMCPMC9334640

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.