Evidence map›Paper›PMID 35902546›Full record

SynthesisReproductive sciences (Thousand Oaks, Calif.)2023

The Association Between Lipid Serum and Semen Parameters: a Systematic Review.

Cennikon Pakpahan, Andri Rezano, Ria Margiana, Bella Amanda, Agustinus Agustinus, Darmadi Darmadi

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Reproductive sciences (Thousand Oaks, Calif.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Effects ofAdvances in pharmacological and pharmaceutical sciences · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Advantages ofOpen veterinary journal · 2024
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cennikon PakpahanAndrology Study Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia. cennikon.pakpahan@fk.unair.ac.id.ORCID 0000-0003-0157-1131
Andri RezanoAndrology Study Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.ORCID 0000-0003-2550-8794
Ria MargianaAndrology Study Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.ORCID 0000-0002-6747-0117
Bella AmandaAndrology Study Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Agustinus AgustinusAndrology Study Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.ORCID 0000-0002-9376-8929
Darmadi DarmadiDepartment of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.ORCID 0000-0001-5281-168X
Airlangga University · IDUniversitas Sumatera Utara · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased lipid levels sometimes not only affect sexual function but also are considered to harm semen quality. It is often a suspicion that elevated lipids are a factor in infertility. We conduct a systematic review. Articles that met the criteria were identified according to The Preferred Reporting Items for Systematic Review and Meta-analysis of recommendations in the PubMed, ProQuest, EBSCO, Web of Science Wiley Online, Springer Link, Scopus, and Science Direct databases with no time restriction for publication. Seven studies are eligible for qualitative analysis from nine studies that have the potential to be assessed. These studies measure the correlation of serum lipids (VLDL, HDL, LDL, triglycerides, total cholesterol, free cholesterol, phospholipids, free fatty acids) with semen parameters (concentration, motility, morphology, DNA fragmentation index). Although not all studies consistently report that lipids impact semen quality, this review suspects that lipids have a significant impact on sperm quality. This study implies that it is necessary to maintain lipid levels to maintain sperm quality and quality of life. However, further investigation with an observational cohort study design needs to be carried out to assess the effect of lipids on semen quality more precisely for the promotion of reproductive health care.

Indexed as

HyperlipidemiasInfertility, MaleLipidsSemenSemen AnalysisSpermatozoaCholesterolHumansMaleQuality of LifeSperm CountSperm MotilityTriglyceridesCholesterolLipidsTriglyceridesLipid serumMale infertilityReproductive health careSperm concentrationSperm morphologySperm motility

Identifiers

PMID35902546
OpenAlexW4288435147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.