Evidence map›Paper›PMID 35902454›Full record

ArticleAAPS PharmSciTech2022

Determination of Alteration in Micromeritic Properties of a Solid Dispersion: Brunauer-Emmett-Teller Based Adsorption and Other Structured Approaches.

Lovepreet Singh, Lakhvir Kaur, Gurjeet Singh, R K Dhawan, Manjeet Kaur, Navdeep Kaur, Prabhpreet Singh

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AAPS PharmSciTech, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lovepreet SinghDepartment of Pharmaceutics, Khalsa College of Pharmacy, Amritsar, Punjab, 143001, India.
Lakhvir KaurDepartment of Pharmaceutics, Khalsa College of Pharmacy, Amritsar, Punjab, 143001, India. lakhvir86@gmail.com.
Gurjeet SinghDepartment of Pharmaceutics, Khalsa College of Pharmacy, Amritsar, Punjab, 143001, India.
R K DhawanDepartment of Pharmacology, Khalsa College of Pharmacy, Amritsar, Punjab, 143001, India.
Manjeet KaurDepartment of Pharmaceutics, Khalsa College of Pharmacy, Amritsar, Punjab, 143001, India.
Navdeep KaurDepartment of Chemistry, Guru Nanak Dev University, Amritsar, Punjab, 143001, India.
Prabhpreet SinghDepartment of Chemistry, Guru Nanak Dev University, Amritsar, Punjab, 143001, India.
Government Medical College, Amritsar · INGuru Nanak Dev University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study is focused on the use of solid dispersion technology to triumph over the solubility-related problems of bexarotene which is currently used for treating various types of cancer and has shown potential inhibitory action on COVID-19 main protease and human ACE2 receptors. It is based on comparison of green locust bean gum and synthetic poloxamer as polymers using extensive mechanistic methods to explore the mechanism behind solubility enhancement and to find suitable concentration of drug to polymer ratio to prepare porous 3

Indexed as

Chemistry, PharmaceuticalCOVID-19AdsorptionCalorimetry, Differential ScanningHumansMicroscopy, Electron, ScanningPolymersSolubilitySpectroscopy, Fourier Transform InfraredX-Ray DiffractionPolymersBETDissolution enhancementLocust bean gumLyophilizationSolid dispersion

Identifiers

PMID35902454
PMCPMC9333898
OpenAlexW4288426071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.