Evidence map›Paper›PMID 35902368›Full record

ArticleJournal of occupational and environmental medicine2022

Occupation and Semen Parameters in a Cohort of Fertile Men.

John D Meyer, Charlene Brazil, J Bruce Redmon, Christina Wang, Amy E Sparks, Shanna H Swan

Abstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John D MeyerFrom the Department of Environmental Medicine & Public Health, Icahn School of Medicine at Mount Sinai, New York, New York (Drs Meyer and Swan); Department of Obstetrics and Gynecology (retired), University of California at Davis, Davis, California (Ms Brazil); Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota (Dr Redmon); Division of Endocrinology, Harbor-UCLA Medical Center, David Geffen School of Medicine at UCLA, Torrance, California (Dr Wang); Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, Iowa City, Iowa (Dr Sparks).
Charlene Brazil
J Bruce Redmon
Christina Wang
Amy E Sparks
Shanna H Swan

Funding

US STUDY OF SEMEN QUALITY IN PARTNERS OF PREGNANT WOMENR01ES009916 · NIEHS · UNIVERSITY OF MISSOURI-COLUMBIA · PI SWAN, SHANNA H · 1998 to 2001
$1.1M
Transgenerational work exposures, EDCs and male fertilityR03OH011540 · OH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MEYER, JOHN D · 2018 to 2019
$170k
NIEHS NIH HHS R01 ES009916NIOSH CDC HHS R03 OH011540
6 · The paper itself

Abstract

objectiveWe examined associations between occupation and semen parameters in demonstrably fertile men in the Study for Future Families.

methodsAssociations of occupation and workplace exposures with semen volume, sperm concentration, motility, and morphology were assessed using generalized linear modeling.

resultsLower sperm concentration and motility were seen in installation, maintenance, and repair occupations. Higher exposure to lead, and to other toxicants, was seen in occupations with lower mean sperm concentrations (prevalence ratio for lead: 4.1; pesticides/insecticides: 1.6; solvents: 1.4). Working with lead for more than 3 months was associated with lower sperm concentration, as was lead exposure outside of work.

conclusionsWe found evidence in demonstrably fertile men for reduced sperm quality with lead, pesticide/herbicide, and solvent exposure. These results may identify occupations where protective measures against male reproductive toxicity might be warranted.

Indexed as

HerbicidesInsecticidesPesticidesHumansLeadMaleOccupationsSemenSolventsSpermatozoaSperm CountSperm MotilityHerbicidesInsecticidesLeadPesticidesSolvents

Identifiers

PMID35902368
PMCPMC9529786

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.