Evidence map›Paper›PMID 35901833›Full record

ReviewThe Lancet. Oncology2022

Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup.

Ignace Vergote, Antonio Gonzalez-Martin, Domenica Lorusso, Charlie Gourley, Mansoor Raza Mirza, Jean-Emmanuel Kurtz, Aikou Okamoto, Kathleen Moore, Frédéric Kridelka, Iain McNeish and 21 more

Erratum issuedAbstract readReviewConsensus Statement
In one paragraph

Review in The Lancet. Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 71 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Correlation between progression-free survival and overall survival in patients with ovarian cancer after cytoreductive surgery: a systematic literature review.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023
    Pooled it
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors.

Ignace VergoteBelgium and Luxembourg Gynaecological Oncology Group (BGOG), Leuven, Belgium; University Hospitals Leuven, Leuven, Belgium. Electronic address: ignace.vergote@uzleuven.be.
Antonio Gonzalez-MartinGrupo Español de Cáncer de Ovario (GEICO), Madrid, Spain; Clinica Universidad de Navarra, Madrid, Spain; Program for Solid Tumors at Madrid, and Center for Applied Medical Research (CIMA), Universidad de Navarra, Pamplona, Spain.
Domenica LorussoMulticenter Italian Trials in Ovarian Cancer and Gynecologic Malignancies (MITO), Naples, Italy; Fondazione Policlinico Gemelli IRCCS, Rome, Italy.
Charlie GourleyScottish Gynaecological Cancer Trials Group (SGCTG), Cancer Research UK, Edinburgh, UK; Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Mansoor Raza MirzaNordic Society of Gynecologic Oncology Clinical Trial Unit (NSGO-CTU), Copenhagen, Denmark; Rigshospitalet, Copenhagen, Denmark.
Jean-Emmanuel KurtzGroupe d'Investigateurs National des Etudes des Cancers Ovariens et du Sein (GINECO), Paris, France; Strasbourg Cancer Institute, Strasbourg, France.
Aikou OkamotoJapanese Gynecologic Oncology Group (JGOG), Tokyo, Japan; The Jikei University School of Medicine, Tokyo, Japan.
Kathleen MooreGynecologic Oncology Group-Foundation (GOG-F), Philadelphia, PA, USA; OU Health Stephenson Cancer Center, Oklahoma City, OH, USA.
Frédéric KridelkaBelgium and Luxembourg Gynaecological Oncology Group (BGOG), Leuven, Belgium; Centre Hospitalier Universitaire de Liège, Liège, Belgium.
Iain McNeishNational Cancer Research Institute (NCRI), London, UK; Department of Surgery and Cancer, Imperial College London, London, UK.
Alexander ReussArbeitsgemeinschaft Gynäkologische Onkologie (AGO) Study Group, Munich, Germany; Coordinating Center for Clinical Trials, Philipps University, Marburg, Germany.
Bénédicte VotanAssociation de Recherche Cancers Gynécologiques (ARCAGY)-GINECO, Paris, France.
Andreas du BoisArbeitsgemeinschaft Gynäkologische Onkologie (AGO) Study Group, Munich, Germany; Kliniken Essen Mitte (KEM), Essen, Germany.
Sven MahnerArbeitsgemeinschaft Gynäkologische Onkologie (AGO) Study Group, Munich, Germany; University Hospital, Ludwig Maximilians University, Munich, Germany.
Isabelle Ray-CoquardGroupe d'Investigateurs National des Etudes des Cancers Ovariens et du Sein (GINECO), Paris, France; Centre Leon Berard and University Claude Bernard Lyon I, Lyon, France.
Elise C KohnNational Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Jonathan S BerekWomen's Cancer Research Network-Cooperative Gynecologic Oncology Investigators (WCRN-COGI), Fresno, CA; Stanford Cancer Institute, Stanford, CA, USA.
David S P TanAsia Pacific Gynecologic Oncology Trials Group (APGOT), Seoul, South Korea; Gynecologic Cancer Group Singapore (GCGS), Singapore; Cancer Science Institute, National University of Singapore, Singapore.
Nicoletta ColomboMario Negri Gynecologic Oncology (MaNGO), Milan, Italy; European Institute of Oncology, Milan, Italy; University of Milano-Bicocca, Milan, Italy.
Rongyu ZangShanghai Gynecologic Oncology Group (SGOG), Shanghai, China; Zhongshan Hospital, Fudan University, Shanghai, China.
Nicole ConcinAGO -Austria, Innsbruck, Austria; Kliniken Essen Mitte (KEM), Essen, Germany; Medical University of Innsbruck, Innsbruck, Austria.
Dearbhaile O'DonnellCancer Trials Ireland (CTI), Dublin, Ireland; St James's Hospital, Dublin, Ireland.
Alejandro Rauh-HainGlobal Gynecologic Oncology Consortium (G-GOC), Houston, TX, USA; MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
C Simon HerringtonScottish Gynaecological Cancer Trials Group (SGCTG), Cancer Research UK, Edinburgh, UK; Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Christian MarthAGO -Austria, Innsbruck, Austria; Medical University of Innsbruck, Innsbruck, Austria.
Andres PovedaGrupo Español de Cáncer de Ovario (GEICO), Madrid, Spain; Hospital Quironsalud, Valencia, Spain.
Keiichi FujiwaraGynecologic Cancer Clinical Trials and Investigation Consortium (GOTIC), North Kanto, Japan; Saitama Medical University International Medical Center, Saitama, Japan.
Gavin C E StuartCanadian Cancer Trials Group (CCTG), Kingston, ON, Canada; University of British Columbia, Vancouver, BC, Canada.
Amit M OzaPrincess Margaret Hospital Consortium (PMHC), Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Michael A BookmanGynecologic Oncology Group-Foundation (GOG-F), Philadelphia, PA, USA; San Francisco Medical Center, San Francisco, CA, USA.
participants of the 6th Gynecologic Cancer InterGroup (GCIG) Ovarian Cancer Consensus Conference on Clinical Research

Funding

Obstetrical and Oncological Outcomes Among Reproductive Age Women with Gynecological and Breast CancerK08CA234333 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI RAUH-HAIN, JOSE ALEJANDRO · 2018 to 2022
$1.2M
Intramural NIH HHS Z99 CA999999NCI NIH HHS K08 CA234333
6 · The paper itself

Abstract

The Gynecologic Cancer InterGroup (GCIG) sixth Ovarian Cancer Conference on Clinical Research was held virtually in October, 2021, following published consensus guidelines. The goal of the consensus meeting was to achieve harmonisation on the design elements of upcoming trials in ovarian cancer, to select important questions for future study, and to identify unmet needs. All 33 GCIG member groups participated in the development, refinement, and adoption of 20 statements within four topic groups on clinical research in ovarian cancer including first line treatment, recurrent disease, disease subgroups, and future trials. Unanimous consensus was obtained for 14 of 20 statements, with greater than 90% concordance in the remaining six statements. The high acceptance rate following active deliberation among the GCIG groups confirmed that a consensus process could be applied in a virtual setting. Together with detailed categorisation of unmet needs, these consensus statements will promote the harmonisation of international clinical research in ovarian cancer.

Indexed as

Ovarian NeoplasmsCarcinoma, Ovarian EpithelialFemaleForecastingHumans

Identifiers

PMID35901833
PMCPMC9465953

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.