Evidence map›Paper›PMID 35901427›Full record

ArticlePsychological trauma : theory, research, practice and policy2023

Concurrent and proximal associations among PTSD symptoms, prescription opioid use, and co-use of other substances: Results from a daily monitoring study.

Christal L Badour, Jessica Flores, Caitlyn O Hood, Alyssa C Jones, C Alex Brake, Jordyn M Tipsword, Christopher J Penn, Jesse P McCann

Abstract read
In one paragraph

Article in Psychological trauma : theory, research, practice and policy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christal L BadourDepartment of Psychology, University of Kentucky.ORCID 0000-0001-9985-8418
Jessica FloresDepartment of Psychology, University of Kentucky.
Caitlyn O HoodDepartment of Psychology, University of Kentucky.
Alyssa C JonesDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina.
C Alex BrakeDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University.
Jordyn M TipswordDepartment of Psychology, University of Kentucky.ORCID 0000-0001-8902-9253
Christopher J PennDepartment of Psychology, University of Kentucky.
Jesse P McCannDepartment of Psychology, University of Kentucky.

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
Supplement for Kentucky BIRCWH Program: Training the Next Generation of Women's Health Scholars: Dr. ConnerK12DA035150 · NIDA · UNIVERSITY OF KENTUCKY · PI Thomas E Curry · 2012 to 2026
$9.0M
Research Training in Drug Abuse BehaviorT32DA035200 · NIDA · UNIVERSITY OF KENTUCKY · PI CRAIG R RUSH, William Walton Stoops · 2013 to 2026
$4.4M
Interdisciplinary Training in Alcohol ResearchT32AA027488 · NIAAA · UNIVERSITY OF KENTUCKY · PI Mark T Fillmore, Mark A Prendergast · 2019 to 2026
$2.0M
NCATS NIH HHS UL1 TR001998NIAAA NIH HHS T32 AA027488NIDA NIH HHS K12 DA035150NIDA NIH HHS T32 DA035200
6 · The paper itself

Abstract

objectivePosttraumatic stress disorder (PTSD) and nonmedical prescription opioid use (NMPOU) are linked. Much of the research documenting this association uses cross-sectional or longitudinal designs that describe patterns of use over extended intervals. The present study used a daily monitoring design to examine how daily fluctuations in PTSD symptoms predicted patterns of prescription opioid use (both medical and nonmedical) and co-use of other substances. This approach has distinct advantages for understanding proximal temporal relations between PTSD symptom variation and substance use patterns.

methodForty adults with clinical or subclinical PTSD and past-month NMPOU completed daily measures of PTSD symptoms, physical pain, prescription opioid use, and other substance use for 28 days using a smartphone application.

resultsSame day co-use of prescription opioids and at least one other substance was common. Higher-than-typical PTSD symptoms on a given day (within-person) was associated with an increased likelihood of reporting NMPOU (overall and with co-use of one or more additional substances) on the same day. This association was specific to PTSD alterations in arousal and reactivity symptoms (Criteria E). Neither total PTSD symptoms nor individual PTSD symptom clusters prospectively predicted next-day prescription opioid use (overall or with co-use). Use of prescription opioids also did not predict next-day PTSD symptom severity.

conclusionThis is the first study to demonstrate positive associations between day-to-day fluctuations in PTSD symptoms and NMPOU. Results from the current study also highlight the importance of examining polysubstance use patterns among individuals with PTSD who use prescription opioids. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Indexed as

Opioid-Related DisordersStress Disorders, Post-TraumaticAdultAnalgesics, OpioidCross-Sectional StudiesHumansPrescriptionsAnalgesics, Opioid

Identifiers

PMID35901427
PMCPMC10157500

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.