ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2022
Cumulative burden of symptomatology in patients with gynecologic malignancies undergoing chemotherapy.
Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Sleep disturbance, anxiety, and depression in postoperative ovarian cancer patients: prevalence, associated factors, and symptom interrelationships.Frontiers in oncology · 2026Article
- Effect of cognitive behavioral therapy on cancer-related fatigue and psychological status in ovarian cancer patients: A meta-analysis.World journal of psychiatry · 2025Article
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Authors and funding
11 authors.
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Abstract
objectivePatients with gynecologic malignancies commonly experience distressing symptoms during chemotherapy. This study sought to evaluate whether symptoms accumulated over the course of several chemotherapy cycles, which could provide essential information for planning supportive interventions.
methodPatients with gynecologic malignancies completed questionnaires about fatigue, depressive symptoms, sleep, and physical activity 1 week before and after chemotherapy cycles 1, 3, and 6. Multilevel models examined the effects of time (pre- and postchemotherapy), treatment cycle (1, 3, 6), and their interaction on symptoms. Logistic regression models examined the effects of time, treatment cycle, and their interaction on the proportion of participants exceeding thresholds for clinically meaningful symptomatology.
resultsMost participants (
conclusionsPatients with gynecologic malignancies have high rates of clinically meaningful symptomatology during chemotherapy. Patients may experience a cumulative burden of symptomatology as treatment progresses, which could have therapeutic implications. Early implementation of supportive interventions should be considered to prevent or mitigate cumulative treatment burden. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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