Evidence map›Paper›PMID 35901245›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

An excitatory peri-tegmental reticular nucleus circuit for wake maintenance.

John M Webb, Mingyang Ma, Chen Yin, Louis J Ptáček, Ying-Hui Fu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Mutant βProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John M WebbDepartment of Neurology, University of California, San Francisco, CA 94143.
Mingyang MaDepartment of Neurology, University of California, San Francisco, CA 94143.
Chen YinDepartment of Neurology, University of California, San Francisco, CA 94143.
Louis J PtáčekDepartment of Neurology, University of California, San Francisco, CA 94143.
Ying-Hui FuDepartment of Neurology, University of California, San Francisco, CA 94143.

Funding

Probing genetics and biology of human sleep homeostasisR01NS117929 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PTACEK, LOUIS J. · 2021 to 2025
$3.3M
Investigating the neurocircuitry of sleep duration regulationR01NS104782 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FU, YING-HUI · 2018 to 2022
$3.0M
Probing genetics and biology of human circadian functionR01NS099333 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PTACEK, LOUIS J. · 2017 to 2021
$2.9M
Investigating Genetics of Human Natural Short SleepersR01NS072360 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FU, YING-HUI · 2011 to 2015
$2.2M
NINDS NIH HHS R01 NS072360NINDS NIH HHS R01 NS099333NINDS NIH HHS R01 NS104782NINDS NIH HHS R01 NS117929
6 · The paper itself

Abstract

Sleep is a necessity for our survival, but its regulation remains incompletely understood. Here, we used a human sleep duration gene to identify a population of cells in the peri-tegmental reticular nucleus (pTRN

Indexed as

SleepTegmentum MesencephaliWakefulnessAnimalsHumansHypothalamic Area, LateralMiceNeuronsFNSSpTRNshort sleepsleepwake

Identifiers

PMID35901245
PMCPMC9407645

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.