Evidence map›Paper›PMID 35901116›Full record

ArticlePloS one2022

Benefit of sequential bilateral cochlear implantation in children between 5 to 18 years old: A prospective cohort study.

W J Kleijbergen, M Sparreboom, E A M Mylanus, G de Koning, H W Helleman, P P B M Boermans, J H M Frijns, J L Vroegop, M P van der Schroeff, E E J Gelders and 5 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Timing of bilateral sequential cochlear implantation for children: determination of its benefit.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  5. Long-Term Non-Users of Transcutaneous Auditory Implants: Thirty Years of Experience at a Single Institution.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

W J KleijbergenDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-9858-570X
M SparreboomDepartment of Otorhinolaryngology, Head and Neck Surgery, Hearing and Implants, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID 0000-0002-8557-6353
E A M MylanusDepartment of Otorhinolaryngology, Head and Neck Surgery, Hearing and Implants, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID 0000-0001-7933-9995
G de KoningDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
H W HellemanDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
P P B M BoermansDepartment of Otorhinolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, Leiden, The Netherlands.
J H M FrijnsDepartment of Otorhinolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, Leiden, The Netherlands.
J L VroegopDepartment of Otorhinolaryngology and Head and Neck Surgery, Erasmus Medical Center, Erasmus University, Rotterdam, The Netherlands.
M P van der SchroeffDepartment of Otorhinolaryngology and Head and Neck Surgery, Erasmus Medical Center, Erasmus University, Rotterdam, The Netherlands.
E E J GeldersDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center, Maastricht University, Maastricht, The Netherlands.
E L J GeorgeDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center, Maastricht University, Maastricht, The Netherlands.
M J W LammersDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
W GrolmanBrain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-3524-3526
I StegemanDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
A L SmitDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
University Medical Center Utrecht · NLErasmus MC · NLLeiden University Medical Center · NLMaastricht University · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the benefit of sequential cochlear implantation after a long inter-implantation interval in children with bilateral deafness receiving their second implant between 5 and 18 years of age. STUDY

designProspective cohort-study.

settingTertiary multicenter. PATIENTS: 85 children with bilateral deafness and unilateral implantation receiving a contralateral cochlear implant at the age of 5 to 18 years.

methodThe primary outcomes were speech recognition in quiet and noise (CVC) scores. The secondary outcomes were language outcomes and subjective hearing abilities, all measured before and 12 months after sequential bilateral cochlear implantation. Medians of the paired data were compared using the Wilcoxon signed-rank test. Univariable linear regression analyses was used to analyze associations between variables and performance outcomes.

resultsA significant benefit was found for speech recognition in quiet (96% [89-98] vs 91% [85-96]; p < 0.01) and noise (65% [57-75] vs 54% [47-71]; p = 0.01) in the bilateral CI condition compared to unilateral (n = 75, excluded 10 non-users). No benefit was seen for language outcomes. The subjective sound quality score was statistically significant higher in bilateral compared to the unilateral CI condition. Pre-operative residual hearing level in the ear of the second implant, the inter-implant interval and age at time of second implantation was not significantly associated with performance scores.

conclusionAfter 12 months of use, sequential bilateral cochlear implantation showed improved speech perception in quiet and noise and improved subjective sound quality outcomes in children despite a great inter-implantation interval (median of 8 years [range 1-16 years]).

Indexed as

Cochlear ImplantationCochlear ImplantsSpeech PerceptionAdolescentChildChild, PreschoolHearing Loss, BilateralHumansProspective StudiesTreatment Outcome

Identifiers

PMID35901116
PMCPMC9333257
OpenAlexW4288428526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.