Evidence map›Paper›PMID 35901049›Full record

ArticlePloS one2022

Impact of prenatal maternal psychological distress on fetal biometric parameters in household air pollution-exposed Nigerian women.

Oluwafunmilade Deji-Abiodun, Babatunde Adedokun, Donee Alexander, Anindita Dutta, Tope Ibigbami, John Olamijulo, Dayo Adepoju, Samuel Adekunle, Oladosu Ojengbede, Christopher O Olopade

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02394574 (Household Air Pollution and Pregnancy Outcome), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02394574 nacompletednot on this map

Household Air Pollution and Pregnancy Outcome

TypeinterventionalSponsorUniversity of ChicagoRan2012 to 2015Enrolled307ConditionsPregnancyArmsClean Cookstove, Traditional Cookstove
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. PMAir quality, atmosphere, & health · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Oluwafunmilade Deji-AbiodunDepartment of Medicine and Center for Global Health, University of Chicago, Chicago, IL, United States of America.
Babatunde AdedokunDepartment of Medicine and Center for Global Health, University of Chicago, Chicago, IL, United States of America.
Donee AlexanderDepartment of Medicine and Center for Global Health, University of Chicago, Chicago, IL, United States of America.
Anindita DuttaDepartment of Medicine and Center for Global Health, University of Chicago, Chicago, IL, United States of America.
Tope IbigbamiHealthy Life for All Foundation, University College Hospital, Ibadan, Nigeria.
John OlamijuloHealthy Life for All Foundation, University College Hospital, Ibadan, Nigeria.
Dayo AdepojuHealthy Life for All Foundation, University College Hospital, Ibadan, Nigeria.
Samuel AdekunleHealthy Life for All Foundation, University College Hospital, Ibadan, Nigeria.
Oladosu OjengbedeDepartment of Obstetrics and Gynecology, University of Ibadan, Ibadan, Nigeria.
Christopher O OlopadeDepartment of Medicine and Center for Global Health, University of Chicago, Chicago, IL, United States of America.ORCID 0000-0002-4243-1488
University of Chicago · USUniversity College Hospital, Ibadan · NGUniversity of Ibadan · NG

Funding

Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
NIEHS NIH HHS P30 ES027792
6 · The paper itself

Abstract

rationaleStudies identify prenatal household air pollution (HAP) exposure and maternal psychological distress (PMPD) as independent factors contributing to gestational ill-health and adverse birth outcomes.

objectiveWe investigated the impact of PMPD on fetal biometric parameters (FBP) in HAP-exposed pregnant Nigerian women.

methodsThe randomized controlled trial (RCT; ClinicalTrials.gov NCT02394574) investigated effects of HAP exposure in pregnant Nigerian women (n = 324), who customarily cooked with polluting fuels (firewood or kerosene). Half of the women (intervention group) were given CleanCook ethanol stoves to use for 156 days during the study. Once a month, all women were administered an abridged version of the SF-12v2TM health-related quality of life questionnaire to assess psychological distress. Using mixed effects linear regression models, adjusted for relevant covariates, we analyzed associations between the women's exposure to PM2·5 (particulate matter with an aerodynamic diameter<2·5 microns) from HAP, their PMPD scores, and FBP (ultrasound estimated fetal weight [UEFW], head circumference [HC], abdominal circumference [AC], femur length [FL], biparietal diameter [BPD], estimated gestational age [GA] and intrauterine growth restriction [IUGR]), and birth anthropometric measures (birth weight [BW] and birth length [BL]).

resultsPMPD negatively impacted UEFW, HC, FL, BPD and BL (p<0·05). Controls (kerosene/firewood users) experienced significantly higher PMPD compared with ethanol-stove users (p<0·05). The mediation analysis revealed that the proportion of the outcome (fetal biometrics, birth anthropometrics, IUGR and GA), which can be explained via PMPD by groups (intervention vs. control) after adjusting for confounding variables was 6·2% (0·062). No significant correlation was observed between levels of PM2.5 exposure and PMPD scores.

conclusionsPMPD was an independent mediator of adverse fetal biometric parameters in pregnant women, who were exposed to HAP from burning of firewood/kerosene. Formulating preventative measures to alleviate maternal distress during pregnancy and reducing exposure to HAP is important from public health perspectives.

Indexed as

Air PollutionPsychological DistressBiometryEthanolFemaleFetal DevelopmentFetal Growth RetardationHumansKeroseneMaternal ExposureNigeriaParticulate MatterPregnancyQuality of LifeUltrasonography, PrenatalEthanolKeroseneParticulate Matter

Identifiers

PMID35901049
PMCPMC9333321
OpenAlexW4288437346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.