Evidence map›Paper›PMID 35901042›Full record

ArticlePloS one2022

Urgent air transfers for acute respiratory infections among children from Northern Canada, 2005-2014.

Caitlin Prendergast, Joan Robinson, Chelsea Caya, Maria E Perez Trejo, Iline Guan, Veronica Hébert-Murakami, Justina Marianayagam, Zing-Wae Wong, Celia Walker, David M Goldfarb and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Caitlin PrendergastDepartment of Pediatrics, University of Ottawa, Ottawa, Canada.
Joan RobinsonDepartment of Pediatrics, University of Alberta, Edmonton, Canada.ORCID 0000-0001-9831-5681
Chelsea CayaResearch Institute of the McGill University Health Centre, Montreal, Canada.
Maria E Perez TrejoResearch Institute of the Children's Hospital of Eastern Ontario, Ottawa, Canada.
Iline GuanDivision of Pediatric Infectious Diseases, Department of Pediatrics, Montreal Children's Hospital, Montreal, Canada.
Veronica Hébert-MurakamiDivision of Pediatric Infectious Diseases, Department of Pediatrics, Montreal Children's Hospital, Montreal, Canada.
Justina MarianayagamDepartment of Pediatrics, University of Ottawa, Ottawa, Canada.
Zing-Wae WongDepartment of Pediatrics, University of Alberta, Edmonton, Canada.
Celia WalkerDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
David M GoldfarbDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Nick BarrowmanResearch Institute of the Children's Hospital of Eastern Ontario, Ottawa, Canada.ORCID 0000-0002-4704-9595
Radha JettyDepartment of Pediatrics, University of Ottawa, Ottawa, Canada.
Joanne EmbreeDepartment of Pediatrics, University of Manitoba, Winnipeg, Canada.
Jesse PapenburgDivision of Pediatric Infectious Diseases, Department of Pediatrics, Montreal Children's Hospital, Montreal, Canada.ORCID 0000-0003-4232-871X
Montreal Children's Hospital · CAUniversity of Ottawa · CAChildren's Hospital of Eastern Ontario · CAUniversity of Alberta · CAUniversity of British Columbia · CAMcGill University Health Centre · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of hospitalizations for acute respiratory infections (ARI) among young Indigenous children from Northern Canada is consistently high. ARIs requiring urgent air transfer can be life-threatening and costly. We aimed to describe their epidemiology, estimate age-specific incidences, and explore factors associated with level of care required.

methodsWe undertook a retrospective cohort study of children <5 years old from Northern Canada transferred by urgent air transport for ARI from 2005 through 2014 to 5 pediatric tertiary care centers in Vancouver, Edmonton, Winnipeg, Ottawa and Montreal. Admissions were identified via ARI-related ICD-9/10 coding and forward sortation area. Descriptive statistics and univariable analyses were performed.

resultsAmong 650 urgent air transfers, the majority were from Nunavut (n = 349, 53.7%) or Nunavik (n = 166, 25.5%), <6 months old (n = 372, 57.2%), and without underlying comorbidity (n = 458; 70.5%). Estimated annual tertiary care ARI admission rates in infants <1 year old from Nunavut (40.7/1000) and Nunavik (44.5/1000) were tenfold higher than in children aged 1 to 4 years. Bronchiolitis (n = 333, 51.2%) and pneumonia (n = 208, 32.0%) were the most common primary discharge diagnoses. Nearly half required critical care (n = 316, 48.6%); mechanical ventilation rates ranged from 7.2% to 55.9% across centres. The most common primary pathogen was respiratory syncytial virus (n = 196, 30.1%). Influenza A or B was identified in 35 cases (5.4%) and vaccine-preventable bacterial infections in 27 (4.1%) cases.

interpretationUrgent air transfers for ARI from Northern Canada are associated with high acuity. Variations in levels of care were seen across referral centers, age groups and pathogens.

Indexed as

Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsChildChild, PreschoolHospitalizationHumansIncidenceInfantRetrospective Studies

Identifiers

PMID35901042
PMCPMC9333212
OpenAlexW4288433566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.