ReviewAnnals of medicine2022
Addressing adolescent substance use with a public health prevention framework: the case for harm reduction.
Review in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 49 citations in OpenAlex.
- Efficacy of the Mexican version of the keepin' it REAL school-based prevention program in addressing multi-substance use from early to mid-adolescence.Drug and alcohol dependence · 2025Trial
- Keepin' It REAL-Mantente REAL in Mexico: Longitudinal Examination of Youth Drug Resistance Strategies and Substance Use Among Early Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023Trial
- Adolescent-Centered Cannabis Messaging in Clinical Settings: Preliminary Qualitative Insights From Adolescents for Clinicians.The Permanente journal · 2026Article
- Age, sex, and ethnic differences in substance use and/or substance use disorders among runaway and homeless youth: A meta-analysis and meta-regression.European child & adolescent psychiatry · 2026Review
- Externalized anger as a mediator of harsh parenting and substance use among Appalachian adolescents.Addictive behaviors reports · 2026Article
- What Teens Hear and How They React: Adolescent Perspectives on Substance Use, Sexual Risk, and Sexual Violence Prevention in Primary Care.Behavioral sciences (Basel, Switzerland) · 2026Article
- "Extremely cheap and extremely potent": Fentanyl Knowledge and Risk Practices AmongYoung People in Oregon Who Have Used Non-Prescription Pills.Research square · 2026Article
- Substance Use Screening Among Adolescents: National Dental Practice-Based Research Network Survey.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Implementation and evaluation of a knowledge translation process to optimize the adoption of harm reduction in cannabis use by practitioners working with youth in Quebec: a mixed-methods study.Health research policy and systems · 2025Article
- Beyond Weight Loss: Optimizing GLP-1 Receptor Agonist Use in Children.Children (Basel, Switzerland) · 2025Review
- Harm reduction approaches for the use of benzodiazepines: a scoping review.Harm reduction journal · 2025Article
- Article
- A Narrative Review of Nicotine and Alcohol Addiction Recovery Content on TikTok.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2025Article
- Illicit drug toxicity from opioid, stimulant or sedative use in adolescents: results of a Canadian one-time cross-sectional study.Paediatrics & child health · 2025Article
- Ethical Considerations in Substance Use Treatment for Youth: Assessing Clinical Practices and Policy Frameworks for Potential Harm.Research on child and adolescent psychopathology · 2025Review
- Mixed-methods study on professionals' attitudes toward harm reduction in cannabis use and the development of a knowledge translation plan.Scientific reports · 2025Article
- Exploring Support Preferences for Young Women Who Self-Harm: A Qualitative Study.International journal of environmental research and public health · 2025Article
- Narrative Review: Revised Principles and Practice Recommendations for Adolescent Substance Use Treatment and Policy.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Review
- Adolescent Addictive Behaviors and Subjective Well-Being: The Mediating Role of Mental Health Problems.Psychology research and behavior management · 2025Article
- Supporting adolescents presenting with illicit drug toxicity.Paediatrics & child health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Adolescence is a developmental stage defined in part by risk-taking. Risk-taking is critical to normal development and has important benefits including trying new activities and exploring new relationships. Risk-taking is also associated with the initiation of substance use. Because substance use often begins in adolescence, much focus has been on primary prevention with the goal of preventing initial substance use. Secondary or tertiary prevention approaches, such as counselling to eliminate substance use or offering treatment, are common approaches for adolescents with problematic substance use or a substance use disorder. While this is important, for some adolescents, treatment or cessation of use may not be desired. In these cases, Healthcare Practitioners (HCPs) can offer clear advice that incorporates harm reduction. Harm reduction, which is often applied for adults who use substances, reduces the negative impacts associated with drug use without requiring abstinence. Harm reduction is crucial to keeping adolescents safe and healthy and can offer opportunities for future engagement in treatment. The objective of this review is to describe strategies for integrating harm reduction principles in clinical settings that are developmentally appropriate. A patient-centered, harm reduction approach can validate perceived benefits of substance use, offer strategies to minimise harm, and advise reduction of use and abstinence.KEY MESSAGES:Substance use often begins in adolescence and traditional approaches are often rooted in prevention framework.Harm reduction should be incorporated for adolescents with problematic substance use or a substance use disorder.This review offers strategies for integration of harm reduction principles tailored towards adolescents.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.