Evidence map›Paper›PMID 35900040›Full record

ArticleEuropean journal of haematology2022

Healthcare resource utilization in patients with myeloproliferative neoplasms: A Danish nationwide matched cohort study.

Sarah Friis Christensen, Lise Skovgaard Svingel, Anders Kjaersgaard, Anna Stenling, Bianka Darvalics, Björn Paulsson, Christen Lykkegaard Andersen, Christian Fynbo Christiansen, Jesper Stentoft, Jørn Starklint and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in European journal of haematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 2 countries.

Sarah Friis ChristensenDepartment of Hematology, Zealand University Hospital, Roskilde, Denmark.ORCID https://orcid.org/0000-0003-2178-0440
Lise Skovgaard SvingelDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-4938-037X
Anders KjaersgaardDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark.
Anna StenlingNovartis Sverige AB, Kista, Sweden.
Bianka DarvalicsDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark.
Björn PaulssonNovartis Sverige AB, Kista, Sweden.
Christen Lykkegaard AndersenDepartment of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Christian Fynbo ChristiansenDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark.
Jesper StentoftDepartment of Hematology, Aarhus University Hospital, Aarhus, Denmark.
Jørn StarklintDepartment of Hematology, Holstebro Hospital, Holstebro, Denmark.
Marianne Tang SeverinsenDepartment of Hematology, Aalborg University Hospital, Aalborg, Denmark.ORCID https://orcid.org/0000-0003-0996-1812
Mette Borg ClausenDepartment of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Morten Hagemann HilsøeDepartment of Hematology, Hospital South West Jutland, Esbjerg, Denmark.
Hans Carl HasselbalchDepartment of Hematology, Zealand University Hospital, Roskilde, Denmark.ORCID https://orcid.org/0000-0003-3936-8032
Henrik FrederiksenDepartment of Hematology, Odense University Hospital, Odense, Denmark.ORCID https://orcid.org/0000-0001-8905-0220
Ellen Margrethe MikkelsenDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark.
Marie BakDepartment of Hematology, Zealand University Hospital, Roskilde, Denmark.ORCID https://orcid.org/0000-0002-1511-6749
Aarhus University Hospital · DKCopenhagen University Hospital · DKNovartis (Sweden) · SEZealand University Hospital · DKAalborg University Hospital · DKHospital South West Jutland · DKOdense University Hospital · DKRegional Hospital Holstebro · DKUniversity of Copenhagen · DK

Funding

Novartis
6 · The paper itself

Abstract

Few studies have assessed healthcare resource utilization (HRU) in patients with Philadelphia-negative myeloproliferative neoplasms (MPN) using a matched cohort design. Further, no detailed assessment of HRU in the years preceding an MPN diagnosis exists. We conducted a registry-based nationwide Danish cohort study, including patients with essential thrombocythemia, polycythemia vera, myelofibrosis, and unclassifiable MPN diagnosed between January 2010 and December 2016. HRU data were summarized annually from 2 years before MPN diagnosis until emigration, death, or end of study (December 2017). We included 3342 MPN patients and 32 737 comparisons without an MPN diagnosis, matched on sex, age, region of residence, and level of education. During the study period, the difference in HRU (rate ratio) between patients and matched comparisons ranged from 1.0 to 1.5 for general practitioner contacts, 0.9 to 2.2 for hospitalizations, 0.9 to 3.8 for inpatient days, 1.0 to 4.0 for outpatient visits, 1.3 to 2.1 for emergency department visits, and 1.0 to 4.1 for treatments/examinations. In conclusion, MPN patients had overall higher HRU than the matched comparisons throughout the follow-up period (maximum 8 years). Further, MPN patients had substantially increased HRU in both the primary and secondary healthcare sector in the 2 years preceding the diagnosis.

Indexed as

Myeloproliferative DisordersPolycythemia VeraCohort StudiesDelivery of Health CareDenmarkHumansambulatory carecase-control studiesearly diagnosisepidemiologygeneral practicehealthcare costshealth resourceshospitalizationmyeloproliferative disorderregistries

Identifiers

PMID35900040
PMCPMC9804288
OpenAlexW4288096180

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.