Evidence map›Paper›PMID 35899596›Full record

ArticleStatistics in medicine2022

Bayesian analysis for partly linear Cox model with measurement error and time-varying covariate effect.

Anqi Pan, Xiao Song, Hanwen Huang

Abstract read
In one paragraph

Article in Statistics in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anqi PanDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-4217-3597
Xiao SongDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, USA.ORCID 0000-0001-8191-7352
Hanwen HuangDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, USA.

Funding

Joint Modeling of Longitudinal Physical Activity and Diet Data and SurvivalR21CA239168 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI WANG, CHING-YUN · 2020 to 2021
$464k
Predictive cancer biomarkers: Design and analysis of reproducibility studiesR21CA201207 · NCI · UNIVERSITY OF GEORGIA · PI DOBBIN, KEVIN K, SONG, XIAO · 2016 to 2017
$359k
NCI NIH HHS R21 CA201207NCI NIH HHS R21 CA239168NIH HHS CA239168
6 · The paper itself

Abstract

The Cox proportional hazards model is commonly used to estimate the association between time-to-event and covariates. Under the proportional hazards assumption, covariate effects are assumed to be constant in the follow-up period of study. When measurement error presents, common estimation methods that adjust for an error-contaminated covariate in the Cox proportional hazards model assume that the true function on the covariate is parametric and specified. We consider a semiparametric partly linear Cox model that allows the hazard to depend on an unspecified function of an error-contaminated covariate and an error-free covariate with time-varying effect, which simultaneously relaxes the assumption on the functional form of the error-contaminated covariate and allows for nonconstant effect of the error-free covariate. We take a Bayesian approach and approximate the unspecified function by a B-spline. Simulation studies are conducted to assess the finite sample performance of the proposed approach. The results demonstrate that our proposed method has favorable statistical performance. The proposed method is also illustrated by an application to data from the AIDS Clinical Trials Group Protocol 175.

Indexed as

Models, StatisticalBayes TheoremComputer SimulationHumansLinear ModelsProportional Hazards ModelsBayesian methodsCox modelmeasurement error modelsemiparametric regressiontime-to-event outcometime-varying coefficient

Identifiers

PMID35899596
PMCPMC9489624

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.