Evidence map›Paper›PMID 35899262›Full record

ArticleFrontiers in neurology2022

Olfactory, Auditory, and Vestibular Performance: Multisensory Impairment Is Significantly Associated With Incident Cognitive Impairment.

Jacob C Lucas, Zack Arambula, Alexandra M Arambula, Katherine Yu, Nathan Farrokhian, Linda D'Silva, Hinrich Staecker, Jennifer A Villwock

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Relationship of Multiple Sensory Impairments With Physical Performance in Older Adults in the Study of Muscle, Mobility and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  2. Aroma: Mixed-Initiative AI Assistance for Non-Visual Cooking by Grounding Multimodal Information Between Reality and Videos.Proceedings of the ACM Symposium on User Interface Software and Technology. ACM Symposium on User Interface Software and Technology · 2025
    Article
  3. Sensory and motor deficits as contributors to early cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jacob C LucasDepartment of Otolaryngology- Head and Neck Surgery, University of Kansas School of Medicine, Kansas City, MO, United States.
Zack ArambulaDepartment of Otolaryngology- Head and Neck Surgery, University of Kansas School of Medicine, Kansas City, MO, United States.
Alexandra M ArambulaDepartment of Otolaryngology- Head and Neck Surgery, University of Kansas School of Medicine, Kansas City, MO, United States.
Katherine YuDepartment of Otolaryngology- Head and Neck Surgery, University of Kansas School of Medicine, Kansas City, MO, United States.
Nathan FarrokhianDepartment of Otolaryngology- Head and Neck Surgery, University of Kansas School of Medicine, Kansas City, MO, United States.
Linda D'SilvaDepartment of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, MO, United States.
Hinrich StaeckerDepartment of Otolaryngology- Head and Neck Surgery, University of Kansas School of Medicine, Kansas City, MO, United States.
Jennifer A VillwockDepartment of Otolaryngology- Head and Neck Surgery, University of Kansas School of Medicine, Kansas City, MO, United States.
University of Kansas · USUniversity of Kansas Medical Center · US

Funding

Institutional Career Development CoreKL2TR002367 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI MATTHEW W MOSCONI, NICOLE L NOLLEN · 2017 to 2026
$7.3M
NCATS NIH HHS KL2 TR002367
6 · The paper itself

Abstract

Background: Dysfunction in the olfactory, auditory, and vestibular systems are commonly seen in aging and are associated with dementia. The impact of sensory loss(es) on cognition is not well understood. Our aim was to assess the relationships between performance on objective multisensory testing and quantify the impact of dysfunction on cognition. Methods: Patients presenting with subjective hearing loss presenting to a tertiary care otologic/audiologic clinic were identified and underwent multisensory testing using the Affordable, Rapid Olfactory Measurement Array (AROMA), pure tone audiometric evaluations, and the Timed "Up and Go" test. Cognitive impairment (CI) was assessed Key Results: 180 patients were enrolled. Thirty one percentage ( Conclusion: Dysfunction of the olfactory, auditory, and vestibular systems is associated with a significantly increased risk of CI. The dramatically increased risk of CI with multisensory dysfunction in all three systems indicated that MSD may synergistically contribute to CI.

Indexed as

age-related hearing impairmentAROMAcognitive impairmentMontreal Cognitive Assessment (MoCA)multisensory impairmentolfactory impairmentvestibular impairment

Identifiers

PMID35899262
PMCPMC9309388
OpenAlexW4285012797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.