Evidence map›Paper›PMID 35899019›Full record

ReviewClinical neurophysiology practice2022

Clinical neurophysiology of Parkinson's disease and parkinsonism.

Robert Chen, Alfredo Berardelli, Amitabh Bhattacharya, Matteo Bologna, Kai-Hsiang Stanley Chen, Alfonso Fasano, Rick C Helmich, William D Hutchison, Nitish Kamble, Andrea A Kühn and 6 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical neurophysiology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Transcranial Ultrasound Stimulation of Internal Globus Pallidus Region and Motor Cortex in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026
    Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Characteristics of Swallowing Function in People with Parkinson's Disease: A Scoping Review.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 7 countries.

Robert ChenKrembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Alfredo BerardelliDepartment of Human Neurosciences, Sapienza University of Rome, Italy.
Amitabh BhattacharyaDepartment of Neurology, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore, India.
Matteo BolognaDepartment of Human Neurosciences, Sapienza University of Rome, Italy.
Kai-Hsiang Stanley ChenDepartment of Neurology, National Taiwan University Hospital Hsinchu Branch, Hsinchu, Taiwan.
Alfonso FasanoKrembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Rick C HelmichRadboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Department of Neurology and Centre of Expertise for Parkinson & Movement Disorders, Nijmegen, the Netherlands.
William D HutchisonKrembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Nitish KambleDepartment of Neurology, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore, India.
Andrea A KühnDepartment of Neurology, Movement Disorder and Neuromodulation Unit, Charité - Universitätsmedizin Berlin, Germany.
Antonella MacerolloInstitute of Systems, Molecular and Integrative Biology, University of Liverpool, United Kingdom.
Wolf-Julian NeumannDepartment of Neurology, Movement Disorder and Neuromodulation Unit, Charité - Universitätsmedizin Berlin, Germany.
Pramod Kumar PalDepartment of Neurology, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore, India.
Giulia PaparellaIRCCS Neuromed Pozzilli (IS), Italy.
Antonio SuppaDepartment of Human Neurosciences, Sapienza University of Rome, Italy.
Kaviraja UdupaDepartment of Neurophysiology National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore, India.
National Institute of Mental Health and Neurosciences · INCharité - Universitätsmedizin Berlin · DEIstituto Neurologico Mediterraneo · ITSapienza University of Rome · ITUniversity of Toronto · CANational Taiwan University Hospital · TWRadboud University Medical Center · NLUniversity Health Network · CAWalton Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review is part of the series on the clinical neurophysiology of movement disorders. It focuses on Parkinson's disease and parkinsonism. The topics covered include the pathophysiology of tremor, rigidity and bradykinesia, balance and gait disturbance and myoclonus in Parkinson's disease. The use of electroencephalography, electromyography, long latency reflexes, cutaneous silent period, studies of cortical excitability with single and paired transcranial magnetic stimulation, studies of plasticity, intraoperative microelectrode recordings and recording of local field potentials from deep brain stimulation, and electrocorticography are also reviewed. In addition to advancing knowledge of pathophysiology, neurophysiological studies can be useful in refining the diagnosis, localization of surgical targets, and help to develop novel therapies for Parkinson's disease.

Indexed as

BradykinesiaDeep brain stimulationElectroencephalographyElectromyographyGait and balanceLocal field potentialsLong latency reflexesMicroelectrode recordingTranscranial magnetic stimulationTremor

Identifiers

PMID35899019
PMCPMC9309229
OpenAlexW4283733853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.