Evidence map›Paper›PMID 35898903›Full record

ArticleFrontiers in microbiology2022

Establishing Sterility Assurance for

Zachary Steven Dean, Michael DiNicola, Emily Klonicki, Scott Roberts, Brian Gregory Clement, Lisa Guan

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zachary Steven DeanJet Propulsion Laboratory, California Institute of Technology, Biotechnology and Planetary Protection, Pasadena, CA, United States.
Michael DiNicolaJet Propulsion Laboratory, California Institute of Technology, Systems Modeling, Analysis, and Architectures Group, Pasadena, CA, United States.
Emily KlonickiJet Propulsion Laboratory, California Institute of Technology, Biotechnology and Planetary Protection, Pasadena, CA, United States.
Scott RobertsJet Propulsion Laboratory, California Institute of Technology, Materials Development and Manufacturing Technology Group, Pasadena, CA, United States.
Brian Gregory ClementJet Propulsion Laboratory, California Institute of Technology, Biotechnology and Planetary Protection, Pasadena, CA, United States.
Lisa GuanJet Propulsion Laboratory, California Institute of Technology, Biotechnology and Planetary Protection, Pasadena, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ever-increasing complexity in critical spacecraft hardware and materials has led to the development of new microbial reduction procedures as well as to changes in established processes such as heat microbial reduction (HMR). In the space biology field of Planetary Protection, 500°C for 0.5 s is the current HMR recommendation to reduce microorganisms from flight hardware. However, more studies are needed to effectively determine the microbial reduction capability of high-temperature (more than 200°C), short-duration (under 30 s) heat exposures. One of the many recent microbial reduction bioengineering research avenues harnesses electromagnetic energy for microbial reduction, with previous investigations demonstrating that infrared heaters are capable of the short temperature ramp time required for rapid heating investigations above 200°C. Therefore, this study employed a 6 kW infrared heater to determine the survivability of heat resistant

Indexed as

endosporesheat microbial reductionheat-resistant microorganismsinfrared heatingPlanetary Protectionspacecraft bioburdensurvival modeling

Identifiers

PMID35898903
PMCPMC9309537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.