Evidence map›Paper›PMID 35898742›Full record

ArticleClinical case reports2022

A case of unresectable combined hepatocellular and cholangiocarcinoma treated with atezolizumab plus bevacizumab.

Naoto Saito, Takeshi Hatanaka, Sachi Nakano, Yoichi Hazama, Sachiko Yoshida, Yoko Hachisu, Yoshiki Tanaka, Teruo Yoshinaga, Kenji Kashiwabara, Norio Kubo and 4 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Naoto SaitoDepartment of Gastroenterology Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Takeshi HatanakaDepartment of Gastroenterology Gunma Saiseikai Maebashi Hospital Maebashi Japan.ORCID https://orcid.org/0000-0003-3656-285X
Sachi NakanoDepartment of Gastroenterology Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Yoichi HazamaDepartment of Gastroenterology Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Sachiko YoshidaDepartment of Gastroenterology Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Yoko HachisuDepartment of Gastroenterology Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Yoshiki TanakaDepartment of Gastroenterology Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Teruo YoshinagaDepartment of Gastroenterology Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Kenji KashiwabaraDepartment of Pathology Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Norio KuboDepartment of Surgery Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Yasuo HosouchiDepartment of Surgery Gunma Saiseikai Maebashi Hospital Maebashi Japan.
Hiroki TojimaDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.
Satoru KakizakiDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.ORCID https://orcid.org/0000-0003-0224-7093
Toshio UraokaDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.
Gunma Saiseikai Maebashi Hospital · JPGunma University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 81-year-old man initially underwent right hepatic lobectomy for liver cancer and was pathologically diagnosed with combined hepatocellular and cholangiocarcinoma (CHC). At 13 months after resection, multiple lymph node metastases were observed. We started atezolizumab plus bevacizumab (Atez/Bev), achieving a 7.5-month progression-free survival. Atez/Bev might exhibit efficacy for CHC patients.

Indexed as

anti‐programmed death ligand‐1hepatic resectionimmune checkpoint inhibitorliver cancervascular endothelial growth factor

Identifiers

PMID35898742
PMCPMC9309740
OpenAlexW4287221604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.