Evidence map›Paper›PMID 35898702›Full record

ArticleFrontiers in nanotechnology2022

High-Density, Actively Multiplexed μECoG Array on Reinforced Silicone Substrate.

Iakov Rachinskiy, Liane Wong, Chia-Han Chiang, Charles Wang, Michael Trumpis, John I Ogren, Zhe Hu, Bryan McLaughlin, Jonathan Viventi

Abstract read
In one paragraph

Article in Frontiers in nanotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The speech neuroprosthesis.Nature reviews. Neuroscience · 2024
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Iakov RachinskiyDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
Liane WongMicro-Leads Inc., Somerville, MA, United States.
Chia-Han ChiangDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
Charles WangDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
Michael TrumpisDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
John I OgrenMicro-Leads Inc., Somerville, MA, United States.
Zhe HuMicro-Leads Inc., Somerville, MA, United States.
Bryan McLaughlinMicro-Leads Inc., Somerville, MA, United States.
Jonathan ViventiDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.

Funding

An Implantable and High-Density, Multiplexed Micro-ECoG SystemR43NS102067 · NINDS · MICRO-LEADS, INC. · PI MCLAUGHLIN, BRYAN L · 2017 to 2018
$701k
NINDS NIH HHS R43 NS102067
6 · The paper itself

Abstract

Simultaneous interrogation of electrical signals from wide areas of the brain is vital for neuroscience research and can aid in understanding the mechanisms of brain function and treatments for neurological disorders. There emerges a demand for development of devices with highly conformal interfaces that can span large cortical regions, have sufficient spatial resolution, and chronic recording capability while keeping a small implantation footprint. In this work, we have designed 61 channel and 48 channel high-density, cortical, micro-electrocorticographic electrode arrays with 400 μm pitch on an ultra-soft but durable substrate. We have also developed a custom multiplexing integrated circuit (IC), methods for packaging the IC in a water-tight liquid crystal polymer casing, and a micro-bonding method for attaching the electronics package to the electrode array. With the integrated multiplexer, the number of external wire connections can be reduced to 16 wires, thereby diminishing the invasive footprint of the device. Both the electrode array and IC were tested

Indexed as

actively multiplexedflexible substrateimplanted deviceneural interfaceμECoG

Identifiers

PMID35898702
PMCPMC9310058

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.