Evidence map›Paper›PMID 35898700›Full record

ArticleClinical pathology (Thousand Oaks, Ventura County, Calif.)

Hematological Abnormalities and Comorbidities Are Associated With the Severity of Kidney Disease: A Hospital-Based Cross-Sectional Study in Bangladesh.

Md Ashrafur Rahman, Yeasna Shanjana, Md Shakil Ahmed, Kuldeep Dhama, Mahadi Hasan Fahim, Tarif Mahmud, Arif Anzum Shuvo, Zahid Hossain Milan, Mohammad Saydur Rahman, Arpita Roy and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical pathology (Thousand Oaks, Ventura County, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Md Ashrafur RahmanDepartment of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka, Bangladesh.ORCID https://orcid.org/0000-0003-0146-5312
Yeasna ShanjanaDepartment of Environmental Sciences, North South University, Bashundhara, Dhaka, Bangladesh.
Md Shakil AhmedDepartment of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka, Bangladesh.
Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.
Mahadi Hasan FahimDepartment of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka, Bangladesh.
Tarif MahmudDepartment of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka, Bangladesh.
Arif Anzum ShuvoDepartment of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka, Bangladesh.
Zahid Hossain MilanCritical Care Department, Evercare Hospital, Bashundhara, Dhaka, Bangladesh.
Mohammad Saydur RahmanDepartment of Pharmacy, Jagannath University, Dhaka, Bangladesh.
Arpita RoyDepartment of Biotechnology, Sharda University, Greater Noida, Uttar Pradesh, India.
Mohiuddin Ahmed BhuiyanDepartment of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.
Md Rabiul IslamDepartment of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.ORCID https://orcid.org/0000-0003-2820-3144
North South University · BDUniversity of Asia Pacific · BDIndian Veterinary Research Institute · INJagannath University · BDSharda University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Abnormalities in hematology and comorbidities might have a role in chronic kidney disease (CKD) patients. However, the exact relationships between hematological parameters and the severity of CKD are not well understood. Also, the underlying mechanisms remain under investigation. The present study aimed to evaluate the association of different blood parameters and comorbidities among hospitalized CKD patients in Bangladesh. Methods: The present study enrolled admitted CKD patients at Evercare Hospital Ltd, Dhaka, Bangladesh, from January 1, 2021, to August 1, 2021. For this study, the demographic and clinical information of the patients were collected. Then some routine blood tests for the hematological profile of CKD patients were performed. Finally, several statistical methods were performed and data interpretations were done to evaluate the role of hematological changes on CKD patients. Results: Among 300 patients, early-stage CKD patients (ESCKDP) and advanced-stage CKD patients (ASCKDP) were 153 and 147, respectively. The decreased levels of hemoglobin (Hb) and red blood cell (RBC) in ASCKDP were observed. However, the present study found increased levels of corpuscular Hb in ASCKDP than ESCKDP. Also, the present study noticed correlations between these changes and the severity of CKD. Also, we observed a significant difference in age and body mass index between ESCKDP and ASCKDP. Conclusions: Based on our results, lower Hb and RBC levels may use in assessing the severity and the treatment decisions of CKD patients in the hospital setting. Therefore, our findings may assist with developing a treatment protocol for hospitalized CKD patients.

Indexed as

hematologyhemoglobinKidney diseasekidney failurered blood cellrenal failurerenal insufficiency

Identifiers

PMID35898700
PMCPMC9310280
OpenAlexW4286728459

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.