Evidence map›Paper›PMID 35898689›Full record

ArticleBioMed research international2022

Determination of Therapeutic and Safety Effects of

Mohammed Yosri, Mahmoud M Elaasser, Marwa M Abdel-Aziz, Marwa M Hassan, Abdulmohsen Hussen Alqhtani, Naif Al-Gabri, Ahmed B A Ali, A Pokoo-Aikins, Basma H Amin

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Mohammed YosriThe Regional Center for Mycology and Biotechnology, Al Azhar University, Nasr City, Cairo, Egypt.ORCID https://orcid.org/0000-0001-7225-8658
Mahmoud M ElaasserThe Regional Center for Mycology and Biotechnology, Al Azhar University, Nasr City, Cairo, Egypt.ORCID https://orcid.org/0000-0003-0862-7628
Marwa M Abdel-AzizThe Regional Center for Mycology and Biotechnology, Al Azhar University, Nasr City, Cairo, Egypt.ORCID https://orcid.org/0000-0003-2140-0655
Marwa M HassanAnatomy and Embryology Department, Faculty of Medicine, Helwan University, Egypt.
Abdulmohsen Hussen AlqhtaniAnimal Production Department, Food and Agriculture Sciences College, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-3858-0923
Naif Al-GabriDepartment of Pathology, Faculty of Veterinary Medicine, Thamar University, Yemen.ORCID https://orcid.org/0000-0002-5679-2532
Ahmed B A AliDepartment of Animal and Veterinary Science, Clemson University, SC, USA.ORCID https://orcid.org/0000-0003-1204-4994
A Pokoo-AikinsUS National Poultry Research Center, Toxicology & Mycotoxin Research Unit, USDA, ARS, Athens, GA 30605, USA.ORCID https://orcid.org/0000-0001-9778-3053
Basma H AminThe Regional Center for Mycology and Biotechnology, Al Azhar University, Nasr City, Cairo, Egypt.ORCID https://orcid.org/0000-0002-7448-7654
Al-Azhar University · EGClemson University · USHelwan University · EGKing Saud University · SAThamar University · YEU.S. National Poultry Research Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Materials and Methods: Seventy-Six Wistar Albino rats of either sex randomly divided into six groups (12/each). The inflammation model was done using Complete Freund's Adjuvant in albino rats. The anti-inflammatory activities of the extract were estimated at different dose levels (15.6, 31, and 60 mg/kg) as well as upon using methotrexate (MTX) as a standard drug (0.3 mg/kg). Paw volume and arthritis index scores have been tested in all examined animals' treatments. Histological examination of joints was also performed. Flow cytometric studies were done to isolated osteoclasts. Cytokines assay as well as biochemical testing was done in the examined samples.

Indexed as

ArthritisArthritis, ExperimentalZygophyllumAnimalsAnti-Inflammatory AgentsCytokinesInflammationPlant ExtractsRatsRats, WistarAnti-Inflammatory AgentsCytokinesPlant Extracts

Identifiers

PMID35898689
PMCPMC9314163
OpenAlexW4285801727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.