Evidence map›Paper›PMID 35898519›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2022

Alzheimer's disease diagnosis and management: Perspectives from around the world.

Diana Kerwin, Carla Abdelnour, Paulo Caramelli, Adesola Ogunniyi, Jiong Shi, Henrik Zetterberg, Martin Traber

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Associations of dementia polyexposure scores to Alzheimer's disease endophenotypes in a diverse population.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  5. Review
  6. [Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Facets of language performance in early-onset and late-onset Alzheimer's disease dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Rebalancing Immune Interactions within the Brain-Spleen Axis Mitigates Neuroinflammation in an Aging Mouse Model of Alzheimer's Disease.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 7 countries.

Diana KerwinKerwin Medical Center Dallas Texas USA.
Carla AbdelnourAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya Barcelona Spain.
Paulo CaramelliBehavioral and Cognitive Neurology Research Group, Faculdade de Medicina Universidade Federal de Minas Gerais Belo Horizonte Brazil.
Adesola OgunniyiUniversity of Ibadan University College Hospital Ibadan Nigeria.
Jiong ShiLou Ruvo Center for Brain Health Cleveland Clinic Las Vegas Nevada USA.
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology the Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.
Martin TraberF. Hoffmann-La Roche Ltd Basel Switzerland.
Cleveland Clinic · USInstituto de Salud Carlos III · ESRoche (Switzerland) · CHSt. Mary-Corwin Medical Center · USUK Dementia Research Institute · GBUniversidade Federal de Minas Gerais · BRUniversity of Ibadan · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) and other dementias are a global challenge. Early diagnosis is important to manage the disease. However, there are barriers to diagnosis that differ by region. Researchers from Brazil, China, Nigeria, Spain, and Sweden have identified key barriers to AD diagnosis in their countries. In Brazil, socioeconomic inequalities and poor recognition of dementia by physicians can prevent diagnosis. In China, a very large population and lack of physician training in dementia make diagnosis problematic. In Nigeria, socioeconomic inequalities and cultural stigma can stand in the way of diagnosis. In Spain, patient hesitancy and an overloaded health-care system are barriers to diagnosis. In Sweden, inconsistent use of biomarkers is a prominent barrier to diagnosis of AD. To support diagnosis, more focus is needed on education of patients and physicians, increased use of support services, and improved access to biomarkers to accurately diagnose AD.

Indexed as

Alzheimer's diseasebiomarkersBrazilChinaNigeriasocioeconomic inequalitiesSpainSweden

Identifiers

PMID35898519
PMCPMC9309007
OpenAlexW4286821205

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.