Evidence map›Paper›PMID 35898458›Full record

ArticleFrontiers in endocrinology2022

An Elevated METS-IR Index Is Associated With Higher Asthma Morbidity and Earlier Age of First Asthma in US Adults: Results Based on a Cross-Sectional Study.

Yan Chen, Junping Yang, Kexing Han, Yan Wang, Cuixia Zhuang, Laxiang Zhu, Mingwei Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yan ChenDepartment of General Practice, Wuhu City Second People's Hospital, Wuhu, China.
Junping YangDepartment of General Practice, Wuhu City Second People's Hospital, Wuhu, China.
Kexing HanDepartment of Infectious Diseases, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Yan WangDepartment of General Practice, Wuhu City Second People's Hospital, Wuhu, China.
Cuixia ZhuangDepartment of General Practice, Wuhu City Second People's Hospital, Wuhu, China.
Laxiang ZhuDepartment of General Practice, Wuhu City Second People's Hospital, Wuhu, China.
Mingwei ChenDepartment of Endocrinology, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Wuhu Fourth People Hospital · CNFirst Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The purpose of this study was to evaluate whether there is a correlation between the METS-IR index and asthma among Americans. Methods: In an attempt to establish the relationship between the METS-IR index and asthma prevalence and age at first onset of asthma, we conducted a logistic regression analysis, subgroup analysis, and dose-response curve analysis using the National Health and Nutrition Examination Survey (NHANES) database. Results: In model 3, each unit increase in METS-IR index led to 1.5% increase in asthma prevalence (OR= 1.015, 95% CI: 1.012, 1.018) and an earlier age of onset of asthma by 0.057years (β= -0.057, 95% CI: -0.112, -0.002).Stratified analysis determined that an increase in METS-IR index was associated with asthma prevalence in almost all subgroups, except in the group where it was not known whether a blood relative had asthma, and a positive linear relationship was found between METS-IR index and asthma prevalence, as well as a linear negative relationship with age at asthma onset. Conclusion: Despite the fact that a direct causal relationship cannot be demonstrated, a higher METS-IR index is positively related to asthma prevalence and correspondingly may result in asthma onset at younger ages.

Indexed as

AsthmaInsulin ResistanceMetabolic SyndromeAdultCross-Sectional StudiesHumansInfant, NewbornMorbidityNutrition SurveysUnited Statesasthma onset ageasthma prevalencecross-sectional studymetabolic syndromeMETS-IR indexNHANES

Identifiers

PMID35898458
PMCPMC9309520
OpenAlexW4285011227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.