Evidence map›Paper›PMID 35898333›Full record

ArticleFood chemistry. Molecular sciences2022

Molecular networking-based lipid profiling and multi-omics approaches reveal new contributions of functional vanilloids to gut microbiota and lipometabolism changes.

Hiroyuki Hattori, Akihiro Moriyama, Tomoki Ohno, Takahiro Shibata, Hitoshi Iwahashi, Tohru Mitsunaga

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry. Molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hiroyuki HattoriAsian Satellite Campuses Institute, Nagoya University, Nagoya 464-8601, Japan.
Akihiro MoriyamaResearch Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8569, Japan.
Tomoki OhnoFaculty of Applied Biological Sciences, Gifu University, Gifu 501-1193, Japan.
Takahiro ShibataGraduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Hitoshi IwahashiFaculty of Applied Biological Sciences, Gifu University, Gifu 501-1193, Japan.
Tohru MitsunagaFaculty of Applied Biological Sciences, Gifu University, Gifu 501-1193, Japan.
Gifu University · JPNagoya University · JPNational Institute of Advanced Industrial Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is now recognized as an epidemic, requiring rapid intervention. We previously demonstrated that vanilloids from the African spice known as Grains of Paradise (GOP) exhibit strong anti-obesity effects. Here, the molecular mechanism behind the obesity prevention property of the GOP extract was investigated by employing molecular networking-based lipid profiling and 16S rRNA sequencing. Administration of either GOP extract or two of its components, 6-paradol and 6-gingerol, reversed the unbalanced gut microbiota composition induced by a high-fat diet (HFD) with a decrease in Firmicutes / Bacteroidetes ratio and increase in genera

Indexed as

16S rRNA gene amplicon sequencingAnti-obesityGrains of paradiseGut microbiotaLipid molecular networkingVanilloid

Identifiers

PMID35898333
PMCPMC9309231
OpenAlexW4285736407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.