Evidence map›Paper›PMID 35897953›Full record

ArticleMolecules (Basel, Switzerland)2022

Ultrasound-Assisted Synthesis and In Silico Modeling of Methanesulfonyl-Piperazine-Based Dithiocarbamates as Potential Anticancer, Thrombolytic, and Hemolytic Structural Motifs.

Freeha Hafeez, Ameer Fawad Zahoor, Azhar Rasul, Asim Mansha, Razia Noreen, Zohaib Raza, Kulsoom Ghulam Ali, Ali Irfan, Gamal A El-Hiti

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Freeha HafeezDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Ameer Fawad ZahoorDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0003-2127-8848
Azhar RasulDepartment of Zoology, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0001-9669-7364
Asim ManshaDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0001-5659-0562
Razia NoreenDepartment of Biochemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Zohaib RazaDepartment of Pharmacology, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0001-7789-4530
Kulsoom Ghulam AliDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Ali IrfanDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0002-8977-3303
Gamal A El-HitiCornea Research Chair, Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia.ORCID 0000-0001-6675-3126
Government College University, Faisalabad · PKKing Saud University · SA

Funding

King Saud University Cornea Research Chair
6 · The paper itself

Abstract

Piperazine-based dithiocarbamates serve as important scaffolds for numerous pharmacologically active drugs. The current study investigates the design and synthesis of a series of dithiocarbamates with a piperazine unit as well as their biological activities. Under ultrasound conditions, the corresponding piperazine-1-carbodithioates

Indexed as

Antineoplastic AgentsPiperazinesCell SurvivalComputer SimulationPiperazineStructure-Activity RelationshipAntineoplastic AgentsPiperazinePiperazinesanticancerhemolysisin silico modelinglung carcinomapiperazine dithiocarbamatesultrasound

Identifiers

PMID35897953
PMCPMC9369641
OpenAlexW4288068980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.