Evidence map›Paper›PMID 35897952›Full record

ReviewMolecules (Basel, Switzerland)2022

Metabolic Engineering of Shikimic Acid Biosynthesis Pathway for the Production of Shikimic Acid and Its Branched Products in Microorganisms: Advances and Prospects.

Sijia Wu, Wenjuan Chen, Sujuan Lu, Hailing Zhang, Lianghong Yin

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 93 citations in OpenAlex.

  1. Article
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  12. EngineeringBiodesign research · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sijia WuState Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou 311300, China.
Wenjuan ChenState Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou 311300, China.
Sujuan LuShandong Fengjin Biopharmaceuticals Co., Ltd., Yantai 264005, China.
Hailing ZhangCollege of Life Sciences, Yantai University, Yantai 264005, China.
Lianghong YinState Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou 311300, China.
Zhejiang A & F University · CNYantai University · CN

Funding

National Natural Science Foundation of China 31600070National Natural Science Foundation of China 32001836Natural Science Foundation of Shandong Province ZR201911180224Zhejiang Provincial Key Laboratory of Resources Protection and Innovation of Traditional Chinese Medicine 2021E10013
6 · The paper itself

Abstract

The shikimate pathway is a necessary pathway for the synthesis of aromatic compounds. The intermediate products of the shikimate pathway and its branching pathway have promising properties in many fields, especially in the pharmaceutical industry. Many important compounds, such as shikimic acid, quinic acid, chlorogenic acid, gallic acid, pyrogallol, catechol and so on, can be synthesized by the shikimate pathway. Among them, shikimic acid is the key raw material for the synthesis of GS4104 (Tamiflu

Indexed as

Metabolic EngineeringShikimic AcidBiosynthetic PathwaysCatecholsEscherichia coliCatecholsShikimic Acidcatecholchlorogenic acidgallic acidmetabolic engineeringpyrogallolquinic acidshikimate pathwayshikimic acidsynthetic biology technology

Identifiers

PMID35897952
PMCPMC9332510
OpenAlexW4288069276

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.