Evidence map›Paper›PMID 35897948›Full record

ArticleMolecules (Basel, Switzerland)2022

Study of Novel Peptides for Antimicrobial Protection in Solution and on Cotton Fabric.

Petar Todorov, Stela Georgieva, Desislava Staneva, Petia Peneva, Petar Grozdanov, Ivanka Nikolova, Evgenia Vasileva-Tonkova, Ivo Grabchev

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Petar TodorovDepartment of Organic Chemistry, University of Chemical Technology and Metallurgy, 1756 Sofia, Bulgaria.ORCID 0000-0002-8050-0149
Stela GeorgievaDepartment of Analytical Chemistry, University of Chemical Technology and Metallurgy, 1756 Sofia, Bulgaria.ORCID 0000-0001-8519-6214
Desislava StanevaDepartment of Textile and Leathers, University of Chemical Technology and Metallurgy, 1756 Sofia, Bulgaria.ORCID 0000-0001-7556-1222
Petia PenevaDepartment of Organic Chemistry, University of Chemical Technology and Metallurgy, 1756 Sofia, Bulgaria.
Petar GrozdanovThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0003-2788-382X
Ivanka NikolovaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-9130-6600
Evgenia Vasileva-TonkovaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Ivo GrabchevFaculty of Medicine, Sofia University "St. Kl. Ohridski", 1407 Sofia, Bulgaria.ORCID 0000-0001-7204-8183
University of Chemical Technology and Metallurgy · BGBulgarian Academy of Sciences · BGSofia University "St. Kliment Ohridski" · BG

Funding

Bulgarian National Scientific Fund КП-06-ДК1/11
6 · The paper itself

Abstract

Some new N- and C-modified biomolecular peptide analogues of both VV-hemorphin-5 and VV-hemorphin-7 with varied amino acids (Cys, Glu, His), 1-adamantanecarboxylic acid, and niacin (nicotinic acid) were synthesized by solid-phase peptide synthesis-Fmoc (9-fluorenylmethoxy-carbonyl) chemistry and were characterized in water solutions with different pH using spectroscopic and electrochemical techniques. Basic physicochemical properties related to the elucidation of the peptide structure at physiological pH have been also studied. The results showed that the interaction of peptide compounds with light and electricity preserves the structural and conformational integrity of the compounds in the solutions. Moreover, textile cotton fibers were modified with the new compounds and the binding of the peptides to the surface of the material was proved by FTIR and SEM analysis. Washing the material with an alkaline soap solution did not show a violation of the modified structure of the cotton. Antiviral activity against the human respiratory syncytial virus (HRSV-S2) and human adenovirus serotype 5 (HAdV-5), the antimicrobial activity against

Indexed as

Anti-Infective AgentsGram-Negative BacteriaAnti-Bacterial AgentsCotton FiberGram-Positive BacteriaHumansTextilesAnti-Bacterial AgentsAnti-Infective Agentsabsorptionantimicrobial peptidesantiviral activitycotton fabricemissionhemorphins

Identifiers

PMID35897948
PMCPMC9332204
OpenAlexW4288068929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.