Evidence map›Paper›PMID 35897869›Full record

ArticleMolecules (Basel, Switzerland)2022

Structure-Based Bioisosterism Design, Synthesis, Biological Activity and Toxicity of 1,2,4-Oxadiazole Substituted Benzamides Analogues Containing Pyrazole Rings.

Min-Ting Tu, Ying-Ying Shao, Sen Yang, Bin-Long Sun, Ying-Ying Wang, Cheng-Xia Tan, Xue-Dong Wang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Min-Ting TuCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.
Ying-Ying ShaoCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.
Sen YangCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.
Bin-Long SunCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.
Ying-Ying WangCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.
Cheng-Xia TanCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China.ORCID 0000-0003-1000-8578
Xue-Dong WangSchool of Environmental Science and Engineering, Suzhou University of Science and Technology, Suzhou 215009, China.

Funding

Siga Co. Ltd. R&D Program KYY-HX-20210049Wynca Group KYY-HX-20200138
6 · The paper itself

Abstract

In order to discover pesticidal lead compounds with high activity and low toxicity, a series of novel benzamides substituted with pyrazole-linked 1,2,4-oxadiazole were designed via bioisosterism. The chemical structures of the target compounds were confirmed via

Indexed as

InsecticidesMothsAnimalsBenzamidesDrug DesignMolecular StructureOxadiazolesPyrazolesStructure-Activity RelationshipZebrafishBenzamidesInsecticidesOxadiazolesPyrazoles1,2,4-oxadiazolebenzamide compoundsbiological activitypyrazolesynthesis

Identifiers

PMID35897869
PMCPMC9330712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.