Evidence map›Paper›PMID 35897744›Full record

ArticleInternational journal of molecular sciences2022

STABILON, a Novel Sequence Motif That Enhances the Expression and Accumulation of Intracellular and Secreted Proteins.

Zsuzsanna Rethi-Nagy, Edit Abraham, Katalin Udvardy, Eva Klement, Zsuzsanna Darula, Margit Pal, Robert L Katona, Vilmos Tubak, Tibor Pali, Zoltan Kota and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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  9. Review
  10. Evolution of insect innate immunity through domestication of bacterial toxins.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. Protein expression/secretion boost by a novel unique 21-mer cis-regulatory motif (Exin21) via mRNA stabilization.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zsuzsanna Rethi-NagyBiological Research Centre, Institute of Biochemistry, MTA SZBK Lendület Laboratory of Cell Cycle Regulation, ELKH, H-6726 Szeged, Hungary.
Edit AbrahamBiological Research Centre, Institute of Biochemistry, MTA SZBK Lendület Laboratory of Cell Cycle Regulation, ELKH, H-6726 Szeged, Hungary.
Katalin UdvardyBiological Research Centre, Institute of Biochemistry, MTA SZBK Lendület Laboratory of Cell Cycle Regulation, ELKH, H-6726 Szeged, Hungary.
Eva KlementSingle Cell Omics Advanced Core Facility, Hungarian Centre of Excellence for Molecular Medicine (HCEMM), H-6726 Szeged, Hungary.
Zsuzsanna DarulaSingle Cell Omics Advanced Core Facility, Hungarian Centre of Excellence for Molecular Medicine (HCEMM), H-6726 Szeged, Hungary.
Margit PalBiological Research Centre, Institute of Biochemistry, MTA SZBK Lendület Laboratory of Cell Cycle Regulation, ELKH, H-6726 Szeged, Hungary.
Robert L KatonaINPAMAC Zrt, H-6723 Szeged, Hungary.
Vilmos TubakCreative Laboratory Ltd., H-6726 Szeged, Hungary.
Tibor PaliBiological Research Centre, Institute of Biophysics, ELKH, H-6726 Szeged, Hungary.ORCID 0000-0003-1649-1097
Zoltan KotaBiological Research Centre, Institute of Biophysics, ELKH, H-6726 Szeged, Hungary.
Rita SinkaDepartment of Genetics, University of Szeged, H-6726 Szeged, Hungary.
Andor UdvardyBiological Research Centre, Institute of Biochemistry, MTA SZBK Lendület Laboratory of Cell Cycle Regulation, ELKH, H-6726 Szeged, Hungary.
Zoltan LipinszkiBiological Research Centre, Institute of Biochemistry, MTA SZBK Lendület Laboratory of Cell Cycle Regulation, ELKH, H-6726 Szeged, Hungary.ORCID 0000-0002-2067-0832
HUN-REN Szegedi Biológiai Kutatóközpont · HUUniversity of Szeged · HU

Funding

Aron Marton College NAEU Horizon 2020 SGA 739593Forerunner Federation NAHungarian Academy of Sciences BO/00329/15Hungarian Academy of Sciences LP2017-7/2017Ministry of Human Capacities of Hungary NTP-NFTÖ-21-B-0221National Research, Development and Innovation Office K132155
6 · The paper itself

Abstract

The dynamic balance of transcriptional and translational regulation together with degron-controlled proteolysis shapes the ever-changing cellular proteome. While a large variety of degradation signals has been characterized, our knowledge of

Indexed as

Drosophila ProteinsProteasome Endopeptidase ComplexAmino Acid MotifsAnimalsDrosophilaMammalsProteolysisUbiquitinDrosophila ProteinsProteasome Endopeptidase ComplexUbiquitinenhancermRNA stabilitypolyubiquitin receptorproteasomeprotein degradationprotein productionprotein stabilitysecreted proteinsstabilization motif

Identifiers

PMID35897744
PMCPMC9332151
OpenAlexW4287835416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.