ReviewInternational journal of molecular sciences2022
High-Density Lipoproteins: A Role in Inflammation in COPD.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Epicardial adipose tissue in patients with chronic obstructive pulmonary disease: systematic review with meta‑analysis and trial sequential analysis.BMC pulmonary medicine · 2023Pooled it
- Article
- Multi-omics integration identifies associations between large high-density lipoprotein and lung function, asthma, and COPD: evidence from genetic and population-based analyses.Respiratory research · 2026Article
- Proteomic Profiling of Pulmonary Function and Cardiovascular Disease Risk in the Atherosclerosis Risk in Communities Study.Journal of the American Heart Association · 2026Observational
- Association between non-HDL-cholesterol to HDL-cholesterol ratio (NHHR) and COPD: a cross-sectional study of 11,082 Chinese adults with predictive nomogram development.BMC pulmonary medicine · 2026Article
- Research Progress on Animal Models of Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2026Review
- Association of the high-density lipoprotein cholesterol to C-reactive protein ratio with chronic cough in US adults: Effect modification by smoking status.Tobacco induced diseases · 2026Article
- Nonlinear thresholds in lipid-frailty interplay: Precision targets for severe airflow limitation in aging adults.PloS one · 2026Article
- Associations of LDL and HDL cholesterol with lung function decline and risk of airflow obstruction in a community-based cohort.Scientific reports · 2025Observational
- Association between high-density lipoprotein cholesterol-related inflammation indices and chronic obstructive pulmonary disease: a cross-sectional study employing machine learning analysis.Lipids in health and disease · 2025Article
- Association between multimarkers of metabolic malnutrition and inflammation and risk of chronic obstructive pulmonary disease and lung function: a prospective cohort study of UK biobank.Nutrition & metabolism · 2025Article
- U-shaped association between lymphocyte-to-high-density lipoprotein ratio and all-cause mortality in patients with chronic obstructive pulmonary disease: insights from a population-based cohort study.Journal of thoracic disease · 2025Article
- Review
- Associations between serum lipid profiles and the incidence of chronic obstructive pulmonary disease in the UK Biobank.Journal of health, population, and nutrition · 2025Article
- The higher serum uric acid to high-density lipoprotein cholesterol ratio is associated with increased risk of chronic obstructive pulmonary disease: result from NHANES 2011-2018.BMC pulmonary medicine · 2025Article
- Linking Lipid Metabolism and Immune Function: New Insights into Chronic Respiratory Diseases.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025Review
- The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and preserved ratio impaired spirometry: NHANES 2007-2012.Lipids in health and disease · 2025Article
- Association between monocyte-high-density lipoprotein cholesterol ratio and mortality in a population with asthma: a cohort study.Lipids in health and disease · 2025Article
- Prognostic Value of Apolipoprotein E in Predicting One-year Mortality in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2025Article
- Association Between the Non-High-Density Lipoprotein Cholesterol-to-High-Density Lipoprotein Cholesterol Ratio (NHHR) and Mortality in Patients with COPD: Evidence From the NHANES 1999-2018.International journal of chronic obstructive pulmonary disease · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic obstructive pulmonary disease (COPD) is a widespread disease associated with high rates of disability and mortality. COPD is characterized by chronic inflammation in the bronchi as well as systemic inflammation, which contributes significantly to the clinically heterogeneous course of the disease. Lipid metabolism disorders are common in COPD, being a part of its pathogenesis. High-density lipoproteins (HDLs) are not only involved in lipid metabolism, but are also part of the organism's immune and antioxidant defense. In addition, HDL is a versatile transport system for endogenous regulatory agents and is also involved in the removal of exogenous substances such as lipopolysaccharide. These functions, as well as information about lipoprotein metabolism disorders in COPD, allow a broader assessment of their role in the pathogenesis of heterogeneous and comorbid course of the disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.