Evidence map›Paper›PMID 35897674›Full record

ArticleInternational journal of molecular sciences2022

Protocadherin Gamma C3 (PCDHGC3) Is Strongly Expressed in Glioblastoma and Its High Expression Is Associated with Longer Progression-Free Survival of Patients.

Jonas Feldheim, David Wend, Mara J Lauer, Camelia M Monoranu, Martin Glas, Christoph Kleinschnitz, Ralf-Ingo Ernestus, Barbara M Braunger, Patrick Meybohm, Carsten Hagemann and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  6. Anti-HER2-targeted therapies: effects on humanFrontiers in drug delivery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jonas FeldheimSection Experimental Neurosurgery, Department of Neurosurgery, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-7297-4854
David WendSection Experimental Neurosurgery, Department of Neurosurgery, University Hospital Würzburg, 97080 Würzburg, Germany.
Mara J LauerDepartment of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-2917-9951
Camelia M MonoranuDepartment of Neuropathology, Institute of Pathology, Julius-Maximilians-University Würzburg, 97080 Würzburg, Germany.
Martin GlasCenter for Translational Neuro- and Behavioral Sciences, University Hospital Essen, 45147 Essen, Germany.
Christoph KleinschnitzCenter for Translational Neuro- and Behavioral Sciences, University Hospital Essen, 45147 Essen, Germany.
Ralf-Ingo ErnestusSection Experimental Neurosurgery, Department of Neurosurgery, University Hospital Würzburg, 97080 Würzburg, Germany.
Barbara M BraungerInstitute of Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, 97070 Würzburg, Germany.
Patrick MeybohmDepartment of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-2666-8696
Carsten HagemannSection Experimental Neurosurgery, Department of Neurosurgery, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-9759-8149
Malgorzata BurekDepartment of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-6148-2195
Universitätsklinikum Würzburg · DEEssen University Hospital · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protocadherins (PCDHs) belong to the cadherin superfamily and represent the largest subgroup of calcium-dependent adhesion molecules. In the genome, most PCDHs are arranged in three clusters,

Indexed as

Brain NeoplasmsCadherin Related ProteinsGlioblastomaGliomaCadherinsHumansProgression-Free SurvivalProtocadherinsRNA, MessengerCadherin Related ProteinsCadherinsPCDHGC3 protein, humanProtocadherinsRNA, Messengerastrocytomabrainexpressionglioblastoma multiformegliomamRNAPCDHGC3proteinrecurrencerelapseWNT signaling

Identifiers

PMID35897674
PMCPMC9330298
OpenAlexW4286587274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.