ArticleMaterials (Basel, Switzerland)2022
Hydroxyapatite from Natural Sources for Medical Applications.
Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 40 citations in OpenAlex.
- Comparative Study on the Surface Properties of Synthetic Carbonated Hydroxyapatite and Natural Hydroxyapatite Before and After Contact with Solutions with de- and Remineralization Activity.Biomimetics (Basel, Switzerland) · 2026Article
- Biocompatible Thin Films Deposited by Laser Techniques.Materials (Basel, Switzerland) · 2026Review
- Study of New Glass-Ceramic and Dense Ceramic Containing Biogenic Hydroxyapatite.Materials (Basel, Switzerland) · 2025Article
- Green Synthesis of Multi-Walled Carbon Nanotube-Reinforced Hydroxyapatite Doped with Silver and Silver-Core Selenium-Shell Nanoparticles: Synthesis, Characterization, and Biological Activity.Nanomaterials (Basel, Switzerland) · 2025Article
- 3D scaffold of hydroxyapatite/β tricalcium phosphate from mussel shells: Synthesis, characterization and cytotoxicity.Heliyon · 2025Article
- Preparation and characterization of highly crystalline hydroxyapatite (HAp) from the scales of an anadromous fish (RSC advances · 2024Article
- Natural hydroxyapatite-based nanobiocomposites and their biomaterials-to-cell interaction for bone tissue engineering.Discover nano · 2024Review
- Microwave Hybrid Sintering and Soldering of Cu-Cr-W Composite Material for Reactive Power Breakers.Materials (Basel, Switzerland) · 2024Article
- Sheep Bone Ultrastructure Analyses Reveal Differences in Bone Maturation around Mg-Based and Ti Implants.Journal of functional biomaterials · 2024Article
- An Eco-Friendly Process to Extract Hydroxyapatite from Sheep Bones for Regenerative Medicine: Structural, Morphologic and Electrical Studies.Journal of functional biomaterials · 2023Article
- Surface Treatment of Mongolian Scots Pine Using Phosphate Precipitation for Better Performance of Compressive Strength and Fire Resistance.Materials (Basel, Switzerland) · 2023Article
- Preparation, Characterization, and Biological Properties of Hydroxyapatite from Bigeye Snapper (International journal of molecular sciences · 2023Article
- Study on the influence of scaffold morphology and structure on osteogenic performance.Frontiers in bioengineering and biotechnology · 2023Review
- Preparation of Collagen/Hydroxyapatite Composites Using the Alternate Immersion Method and Evaluation of the Cranial Bone-Forming Capability of Composites Complexed with Acidic Gelatin and b-FGF.Materials (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
The aim of this work is to study the physical-chemical, mechanical, and biocompatible properties of hydroxyapatite obtained by hydrothermal synthesis, at relatively low temperatures and high pressures, starting from natural sources (Rapana whelk shells), knowing that these properties influence the behavior of nanostructured materials in cells or tissues. Thus, hydroxyapatite nanopowders were characterized by chemical analysis, Fourier-transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS), scanning electron microscopy (SEM), and X-ray diffraction (XRD). In vitro studies on osteoblast cell lines (cytotoxicity and cell proliferation), as well as preliminary mechanical tests, have been performed. The results showed that the obtained powders have a crystallite size below 50 nm and particle size less than 100 nm, demonstrating that hydrothermal synthesis led to hydroxyapatite nanocrystalline powders, with a Ca:P ratio close to the stoichiometric ratio and a controlled morphology (spherical particle aggregates). The tensile strength of HAp samples sintered at 1100 °C/90 min varies between 37.6-39.1 N/mm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.