ArticleMicrobiome2022
Supercarriers of antibiotic resistome in a world's large river.
Article in Microbiome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Role of extended-spectrum β-lactamase (ESBL) genes in the dissemination of β-lactam resistance within aquatic environments: mechanisms, persistence, and one health implications.World journal of microbiology & biotechnology · 2026Review
- Contrasting Roles of Mobile Genetic Elements and Metal Resistance Genes in Shaping the Gut Resistome of Wild Fish from the Qiantang River.Animals : an open access journal from MDPI · 2026Article
- Article
- Nitrate-reducing bacteria bridge nitrogen cycling and antibiotic resistance in river ecosystems.Nature communications · 2026Article
- Deciphering the drivers of antibiotic resistance gene transmission in the megacity: Co-occurring contaminants and bacterial community.Eco-Environment & Health · 2026Article
- Resistome flow in global landfill systems.iMetaOmics · 2026Article
- Colored Plastic Pollution Reshapes Aquatic Microbial Community and Resistance Profile via Divergent Pseudonatural Dissolved Organic Matter.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Metagenomic insights into antibiotic resistance genes and virulence factors in sediments of river Yamuna.Frontiers in microbiology · 2026Article
- Effects of predatory mite biocontrols on the dispersal of antibiotic resistomes and virulence factors in tea garden soils.Microbiome · 2025Article
- Long-term exposure to polyethylene restructures the multi-kingdom soil microbiota in maize fields.Communications biology · 2025Article
- Nano-biochar regulates phage-host interactions, reducing antibiotic resistance genes in vermicomposting systems.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Climate warming fuels the global antibiotic resistome by altering soil bacterial traits.Nature ecology & evolution · 2025Article
- Microbial genomic database of the Yangtze River, the third-longest river on Earth.Scientific data · 2025Article
- Composition, Distribution and Mobility Potential of the Antibiotic Resistome in Sediments from the East China Sea Revealed by Metagenomic Analysis.Microorganisms · 2025Article
- A river of resistant genes uncovered by metagenomics.Nature reviews. Microbiology · 2025Article
- Sludge water: a potential pathway for the spread of antibiotic resistance and pathogenic bacteria from hospitals to the environment.Frontiers in microbiology · 2025Article
- Rapid identification of antibiotic resistance gene hosts by prescreening ARG-like reads.Environmental science and ecotechnology · 2025Article
- Health risk ranking of antibiotic resistance genes in the Yangtze River.Environmental science and ecotechnology · 2024Article
- Article
- Dietary supplementation with a novel acidifier sodium diformate improves growth performance by increasing growth-related hormones levels and preventsFrontiers in veterinary science · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntibiotic resistome has been found to strongly interact with the core microbiota in the human gut, yet little is known about how antibiotic resistance genes (ARGs) correlate with certain microbes in large rivers that are regarded as "terrestrial gut."
resultsBy creating the integral pattern for ARGs and antibiotic-resistant microbes in water and sediment along a 4300-km continuum of the Yangtze River, we found that human pathogen bacteria (HPB) share 13.4% and 5.9% of the ARG hosts in water and sediment but contribute 64% and 46% to the total number of planktonic and sedimentary ARGs, respectively. Moreover, the planktonic HPB harbored 79 ARG combinations that are dominated by "natural" supercarriers (e.g., Rheinheimera texasensis and Noviherbaspirillum sp. Root189) in river basins.
conclusionsWe confirmed that terrestrial HPB are the major ARG hosts in the river, rather than conventional supercarriers (e.g., Enterococcus spp. and other fecal indicator bacteria) that prevail in the human gut. The discovery of HPB as natural supercarriers in a world's large river not only interprets the inconsistency between the spatial dissimilarities in ARGs and their hosts, but also highlights the top priority of controlling terrestrial HPB in the future ARG-related risk management of riverine ecosystems globally. Video Abstract.
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