ArticleBMC psychiatry2022
Association of marital status with cognitive function in Chinese hypertensive patients: a cross-sectional study.
Article in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
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11 citing papers in PubMed, 14 citations in OpenAlex.
- Gender Differences in the Association Between Marriage and Cognitive Decline: Evidence From the China Health and Retirement Longitudinal Study (CHARLS).PsyCh journal · 2026Article
- Cognitive impairment and associated factors among community-dwelling older adults with hypertension in tropical China.Frontiers in public health · 2026Article
- Associations between widowhood status/duration, depression, and cognitive function among community-dwelling Indians age 60 years or older: Exploration of sex and residential factors.Social psychiatry and psychiatric epidemiology · 2025Article
- Correction: Association of marital status with cognitive function in Chinese hypertensive patients: a cross-sectional study.BMC psychiatry · 2025Article
- Relationship between social participation and cognitive impairment in low-educated older adults based on Indonesian Family Life Survey-5.Korean journal of family medicine · 2025Article
- Influencing factors, gender differences and the decomposition of inequalities in cognitive function in Chinese older adults: a population-based cohort study.BMC geriatrics · 2024Article
- Longitudinal associations between the frequency of playing Mahjong and cognitive functioning among older people in China: evidence from CLHLS, 2008-2018.Frontiers in public health · 2024Article
- Depressive Symptoms and Cognitive Function in Older Adults: A Cross-Lagged Network Analysis.Depression and anxiety · 2024Article
- Positive association between weight-adjusted-waist index and dementia in the Chinese population with hypertension: a cross-sectional study.BMC psychiatry · 2023Article
- The high burden of symptoms associated with cognitive impairment in lung cancer patients: A latent class analysis.Asia-Pacific journal of oncology nursing · 2023Article
- Inflammation markers and the risk of hypertension in people living with HIV.Frontiers in immunology · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to evaluate the association of marital status with cognitive function and to examine the potential effect modifiers in Chinese hypertensive populations.
methodsA total of 9,525 adult Chinese hypertensive patients were enrolled in this cross-sectional study. Cognitive function, as the dependent variable in our study, was assessed by the Chinese version of the Mini-Mental State Examination (MMSE). We adjusted for potential confounding factors in multiple linear regression models to examine the relationship of marital status with cognitive function. In addition, we divided the population according to sex to explore whether there were sex-specific differences.
resultsAmong the 9,525 study participants, the mean (SD) age for men was 63.5 (10.3) years, and the mean MMSE score was 24.9 ± 5.0, whereas for women, the mean (SD) age was 63.8 (9.3) years, and the mean MMSE score was 19.4 ± 6.4. Unmarried persons had lower scores on the MMSE and lower subscores in each of the cognitive domains. A stronger correlation between marital status and a lower MMSE score was statistically significant in men (unmarried men: β = -1.55; 95% CI: -1.89, -1.21) but not women (unmarried women: β = -0.22; 95% CI: -0.56, 0.12; p interaction = 0.006). Compared to men who were widowed or divorced, never married men were more likely to have lower MMSE scores (β = -2.30, 95% CI -3.10,-1.50; p < 0.001).
conclusionsOur study demonstrated that being unmarried is an extremely important but neglected social risk factor for cognitive function. Sex was a strong effect modifier: being unmarried was correlated with a higher risk of cognitive decline than being married in Chinese hypertensive men, especially among older men, but this correlation was not observed among women. Moreover, never married men showed poorer cognitive function than those who were divorced or widowed.
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