ArticleBMC anesthesiology2022
Multimodal opioid-sparing pain management for emergent cesarean delivery under general anesthesia: a quality improvement project.
Article in BMC anesthesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Retrolaminar versus erector spinae plane block for enhanced recovery after cesarean section: a retrospective study.Perioperative medicine (London, England) · 2026Article
- Adequacy of pain management and its predictors following cesarean section: a longitudinal data analysis using a generalized estimating equation model.Scientific reports · 2026Article
- Recommendations for Perioperative Care in Liver Resection: The EUPEMEN (EUropean PErioperative MEdical Networking) Protocol.Medicina (Kaunas, Lithuania) · 2025Review
- Global research frontiers and thematic trends in opioid-free anesthesia over the past 20 years: a bibliometric analysis.Frontiers in pharmacology · 2025Review
- The EUPEMEN (EUropean PErioperative MEdical Networking) Protocol for Acute Appendicitis: Recommendations for Perioperative Care.Journal of clinical medicine · 2024Article
- Multimodal Analgesia and Outcomes in Hysterectomy Surgery-A Population-Based Analysis.Journal of clinical medicine · 2024Article
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Authors and funding
9 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundOpioid-sparing multimodal analgesic approach has been shown to provide effective postoperative pain relief and reduce postoperative opioid consumption and opioid-associated adverse effects. While many studies have evaluated analgesic strategies for elective cesarean delivery, few studies have investigated analgesic approaches in emergent cesarean deliveries under general anesthesia. The primary aim of this quality improvement project is to evaluate opioid consumption with the use of a multimodal opioid-sparing pain management pathway in patients undergoing emergent cesarean delivery under general anesthesia.
methodsSeventy-two women (age > 16 years) undergoing emergent cesarean delivery under general anesthesia before (n = 36) and after (n = 36) implementation of a multimodal opioid-sparing pain management pathway were included. All patients received a standardized general anesthetic. Prior to implementation of the pathway, postoperative pain management was primarily limited to intravenous patient-controlled opioid administration. The new multimodal pathway included scheduled acetaminophen and non-steroidal anti-inflammatory medications and ultrasound-guided classic lateral transversus abdominis plane blocks with postoperative opioids reserved only for rescue analgesia. Data obtained from electronic records included demographics, intraoperative opioid use, and pain scores and opioid consumption upon arrival to the recovery room, at 2, 6, 12, 24, 48, and 72 h postoperatively.
resultsPatients receiving multimodal opioid sparing analgesia (AFTER group) had lower opioid use for 72 h, postoperatively. Only 2 of the 36 patients (5.6%) in the AFTER group required intravenous opioids through patient-controlled analgesia while 30 out of 36 patients (83.3%) in the BEFORE group required intravenous opioids.
conclusionsMultimodal opioid-sparing analgesia is associated with reduced postoperative opioid consumption after emergent cesarean delivery.
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