ArticleInternational journal of clinical pharmacy2022
Risk factors for potentially inappropriate medication use in older adults: a cohort study.
Article in International journal of clinical pharmacy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Incidence and duration of hospital-initiated opioids, benzodiazepines and antipsychotics: a retrospective cohort study.International journal of clinical pharmacy · 2026Article
- Development of a nomogram for predicting the risk of potentially inappropriate medication use in older adults: A retrospective cross-sectional study.The Journal of international medical research · 2026Article
- Potentially inappropriate medication use among older outpatients-prevalence and contributing factors: a retrospective study.Sao Paulo medical journal = Revista paulista de medicina · 2026Article
- Pharmacist-led deprescribing to improve medication safety in older patients with hip fractures.BMC geriatrics · 2025Article
- Patient-Related Factors Associated With the Initiation of Potentially Inappropriate Medication in Home Care: An Observational Study Based on Resident Assessment Instrument Data.Basic & clinical pharmacology & toxicology · 2025Observational
- Trajectories of potentially inappropriate medication use among older adults in Saudi Arabia.Frontiers in pharmacology · 2025Article
- Potentially Inappropriate Prescribing and Potential Prescribing Omissions and Their Association with Adverse Drug Reaction-Related Hospital Admissions.Journal of clinical medicine · 2024Article
- Potentially Inappropriate Medications in Older Adults-Prevalence, Trends and Associated Factors: A Cross-Sectional Study in Saudi Arabia.Healthcare (Basel, Switzerland) · 2023Article
- Clinical pharmacist intervention to improve medication safety for hip fracture patients through secondary and primary care settings: a nonrandomised controlled trial.Journal of orthopaedic surgery and research · 2023Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundMuch of the knowledge on the use of potentially inappropriate medications (PIM) in older adults is derived from cross-sectional studies, with little known about the risk factors over time.
aimLongitudinal analysis was applied to estimate the occurrence and risk factors of PIM use among older adults in a 10-year follow-up.
methodLongitudinal study with 418 older adult residents of a capital city of Central-West Brazil. The PIM were classified according to the Beers criteria 2019. The usage rate was calculated at baseline (2008) and at the 10-year follow-up moment (2018). Analysis of predictors (sociodemographic, self-rated health, hospitalization, number of comorbidities, polypharmacy, diabetes, hypertension, hypercholesterolemia and nutritional status) was performed using Generalized Estimating Equation (GEE) models.
resultsMean age at baseline was 70.6 years (SD 7.1) and 76% were women; 221 older adults took part in the follow up. The rate of PIM use was 50.4% at baseline and 57.5% at the 10-year follow-up. Multiple analysis showed that PIM use in the cohort was statistically higher in the older adults with a history of hospitalization (RR
conclusionA high level of potentially inappropriate medication use was observed, reaching 50% of the older adults, with a 7% increase in the prevalence over the 10-year follow-up period. Hospitalization, multimorbidities, polypharmacy and diabetes mellitus were associated with the use of these medications. Interventions for surveillance of the deprescribing process need to be encouraged to avoid potential harm caused by the use of medications.
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