Evidence map›Paper›PMID 35896853›Full record

ArticleJournal of behavioral medicine2023

Exploring content of misinformation about HPV vaccine on twitter.

Melanie L Kornides, Sarah Badlis, Katharine J Head, Mary Putt, Joseph Cappella, Graciela Gonzalez-Hernadez

Open access · bronzeAbstract read
In one paragraph

Article in Journal of behavioral medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
18.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Redefining oropharyngeal cancer in the HPV era: integrating precision medicine and immunotherapeutic frontiers.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care.International journal of environmental research and public health · 2025
    Review
  12. Article
  13. Article
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  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Melanie L KornidesDepartment of Family and Community Health, School of Nursing, Department of Pediatrics, Perelman School of Medicine; and Leonard Davis Institute of Health Economics; and Center for Health Incentives and Behavioral Economics, University of Pennsylvania, 418 Curie Blvd, Philadelphia, PA, 19104, USA. kornides@nursing.upenn.edu.ORCID 0000-0003-1900-4530
Sarah BadlisDepartment of Family and Community Health, School of Nursing, Department of Pediatrics, Perelman School of Medicine; and Leonard Davis Institute of Health Economics; and Center for Health Incentives and Behavioral Economics, University of Pennsylvania, 418 Curie Blvd, Philadelphia, PA, 19104, USA.
Katharine J HeadDepartment of Communication Studies, Indiana University-Purdue University Indianapolis, Indianapolis, USA.
Mary PuttDivision of Biostatistics, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.
Joseph CappellaThe Annenberg School for Communication, University of Pennsylvania, Philadelphia, USA.
Graciela Gonzalez-HernadezHealth Language Processing Lab, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.
University of Pennsylvania · USUniversity of Indianapolis · USCommunity Initiatives · US

Funding

Social Media Mining for PharmacovigilanceR01LM011176 · NLM · UNIVERSITY OF PENNSYLVANIA · PI GONZALEZ HERNANDEZ, GRACIELA, SHEN, LI · 2012 to 2021
$4.5M
Training in Sex and Gender Differences Research to Improve Women's HealthK12HD085848 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI OQUENDO, MARIA A · 2015 to 2019
$2.2M
An inoculation theory-based messaging intervention addressing misinformation about HPV vaccine on social media: The Inoculate for HPV Vaccine randomized controlled trialR37CA259210 · NCI · UNIVERSITY OF PENNSYLVANIA · PI KORNIDES, MELANIE LYNN · 2022 to 2025
$1.9M
NCI NIH HHS R37 CA259210NICHD NIH HHS K12 HD085848NLM NIH HHS R01 LM011176
6 · The paper itself

Abstract

Although social media can be a source of guidance about HPV vaccination for parents, the information may not always be complete or accurate. We conducted a retrospective content analysis to identify content and frequencies of occurrence of disinformation and misinformation about HPV vaccine posted on Twitter between December 15, 2019, through March 31, 2020, among 3876 unique, English language #HPV Tweets, excluding retweets. We found that 24% of Tweets contained disinformation or misinformation, and the remaining 76% contained support/education. The most prevalent categories of disinformation/misinformation were (1) adverse health effects (59%), (2) mandatory vaccination (19%), and (3) inefficacy of the vaccine (14%). Among the adverse health effects Tweets, non-specific harm/injury (51%) and death (23%) were most frequent. Disinformation/misinformation Tweets vs. supportive Tweets had 5.44 (95% CI 5.33-5.56) times the incidence rate of retweet. In conclusion, almost one-quarter of #HPV Tweets contained disinformation or misinformation about the HPV vaccine and these tweets received higher audience engagement including likes and retweets. Implications for vaccine hesitancy are discussed.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesSocial MediaCommunicationHumansRetrospective StudiesPapillomavirus VaccinesAdolescent healthDisinformationHPV vaccineMisinformationSocial mediaVaccine hesitancy

Identifiers

PMID35896853
PMCPMC9328646
OpenAlexW4288052440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.