Evidence map›Paper›PMID 35896803›Full record

ArticleEuropean journal of clinical pharmacology2022

Attitudes and beliefs of older adults and caregivers towards deprescribing in French-speaking countries: a multicenter cross-sectional study.

Barbara Roux, Bianca Rakheja, Caroline Sirois, Anne Niquille, Catherine Pétein, Nicole Ouellet, Anne Spinewine, François-Xavier Sibille, Marie-Laure Laroche

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European journal of clinical pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06212713 (Development and Validation of a Health Behaviour Theory-based Questionnaire to Explore the Willingness of Older Adults and Informal Caregivers to Deprescribe), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06212713 unknown statusnot on this mapstarted 2023, after this paper: background citation

Development and Validation of a Health Behaviour Theory-based Questionnaire to Explore the Willingness of Older Adults and Informal Caregivers to Deprescribe

TypeobservationalSponsorUniversité Catholique de LouvainRan2023 to 2024Enrolled600ConditionsPsychologicalArmsQuestionnaire administration
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Barbara RouxCentre of Pharmacovigilance and Pharmacoepidemiology, Department of Pharmacology-Toxicology and Centre of Pharmacovigilance, University Hospital of Limoges, Limoges, France.
Bianca RakhejaFaculty of Medicine, Laval University, Quebec, Canada.
Caroline SiroisFaculty of Pharmacy, Laval University, Quebec, Canada.
Anne NiquilleCenter for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
Catherine PéteinClinical Pharmacy Research Group, Louvain Drug Research Institute, UCLouvain, Brussels, Belgium.
Nicole OuelletDepartment of Health, University of Quebec at Rimouski, Rimouski, Canada.
Anne SpinewineClinical Pharmacy Research Group, Louvain Drug Research Institute, UCLouvain, Brussels, Belgium.
François-Xavier SibilleDepartment of Geriatric Medicine, CHU UCL Namur, Yvoir, Belgium.
Marie-Laure LarocheCentre of Pharmacovigilance and Pharmacoepidemiology, Department of Pharmacology-Toxicology and Centre of Pharmacovigilance, University Hospital of Limoges, Limoges, France. marie-laure.laroche@chu-limoges.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSuccessful deprescribing requires understanding the attitudes of older adults and caregivers towards this process. This study aimed to capture these attitudes in four French-speaking countries and to investigate associated factors.

methodsA multicenter cross-sectional study was conducted by administrating the French version of the revised Patients' Attitudes Towards Deprescribing (rPATD) questionnaire in Belgium, Canada, France, and Switzerland. Community-dwelling or nursing home older adults ≥ 65 years taking ≥ 1 prescribed medications and caregivers of older adults with similar characteristics were included. Multivariate logistic regressions were carried out to examine factors associated with willingness to deprescribe.

resultsA total of 367 older adults (79.3 ± 8.7 years, 63% community-dwelling, 54% ≥ 5 medications) and 255 unrelated caregivers (64.4 ± 12.6 years) of care recipients (83.4 ± 7.9 years, 52% community-dwelling, 69% ≥ 5 medications) answered the questionnaire. Among them, 87.5% older adults and 75.6% caregivers would be willing to stop medications if the physician said it was possible. Reluctance to stop a medication taken for a long time was expressed by 46% of both older adults and caregivers. A low score for the factor "concerns about stopping" (older adults: aOR: 0.21; 95% CI: 0.07-0.59), and a high score for the factor "involvement" (older adults: aOR: 2.66; 95% CI: 1.01-7.07; caregivers: aOR: 11.28; 95% CI: 1.48-85.91) were associated with willingness to deprescribe.

conclusionsA significant proportion of older adults and caregivers of French-speaking countries are open to deprescribing. Despite this apparent willingness, deprescribing conversations in clinical practice remains marginal, emphasizing the importance of optimizing the integration of existing tools such as rPATD.

Indexed as

DeprescriptionsAgedAttitudeCaregiversCross-Sectional StudiesHumansPolypharmacySurveys and QuestionnairesAttitudesCaregiversDeprescribingOlder adultsPolypharmacy

Identifiers

PMID35896803

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.